69 189

Cited 14 times in

Echocardiographically measured epicardial fat predicts restenosis after coronary stenting.

Park, JS; Choi, BJ; Choi, SY; Yoon, MH; Hwang, GS; Tahk, SJ; Shin, JH
Scandinavian cardiovascular journal : SCJ, 47(5):297-302, 2013
Journal Title
Scandinavian cardiovascular journal : SCJ
OBJECTIVE: Epicardial adipose tissue (EAT), deposited around subepicardial coronary vessels, may contribute directly to perivascular inflammation and smooth muscle cell proliferation. This study assessed the relationship between EAT and in-stent restenosis.

METHODS: Four hundred and seven patients had received successful coronary intervention. EAT thickness was measured by echocardiography. Angiographic follow-up was obtained between 6 months and 2 years. Restenosis was defined as target lesion revascularization (TLR). EAT thickness of patients was compared by TLR controlling for additional well-known predictors of restenosis. The TLR-free survival analysis according to EAT thickness was estimated using the Kaplan-Meier method and the differences between groups were assessed by the log-rank test.

RESULTS: Median EAT thickness was significantly increased in patients undergoing TLR compared with those without restenosis (3.7 vs. 3.0 mm, p = 0.001). EAT thickness was one of the independent factors associated with restenosis (Odds ratio = 1.19, 95% confidence interval = 1.01-1.33, p = 0.007). The TLR-free survival of patients with thick EAT was significantly worse than patients with thin EAT (log-rank p = 0.001).

CONCLUSIONS: EAT thickness is related with restenosis and may provide additional information for future restenosis.
MeSH terms
Adipose Tissue/*ultrasonography*AdiposityAgedCoronary Restenosis/*etiologyEchocardiographyFemaleHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedPercutaneous Coronary InterventionPostoperative Complications/etiology/ultrasonographyStents/adverse effects
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
AJOU Authors
박, 진선최, 병주최, 소연윤, 명호황, 교승탁, 승제신, 준한
Full Text Link
Files in This Item:
fulltext not available.txtDownload
RIS (EndNote)
XLS (Excel)


해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.