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Genetics of hypersensitivity to aspirin and nonsteroidal anti-inflammatory drugs.

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dc.contributor.authorKim, SH-
dc.contributor.authorSanak, M-
dc.contributor.authorPark, HS-
dc.date.accessioned2014-05-22T04:35:23Z-
dc.date.available2014-05-22T04:35:23Z-
dc.date.issued2013-
dc.identifier.issn0889-8561-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/10064-
dc.description.abstractVarious hypersensitivity reactions have been reported with aspirin and nonsteroidal anti-inflammatory drugs. Hypersensitivity can occur regardless of a chemical drug structure or its therapeutic potency. Allergic conditions include aspirin-exacerbated respiratory disease (AERD or aspirin-induced asthma), aspirin-induced urticaria/angioedema (AIU), and anaphylaxis. Several genetic studies on aspirin hypersensitivity have been performed to discover the genetic predisposition to aspirin hypersensitivity and to gain insight into the phenotypic diversity. This article updates data on the genetic mechanisms that govern AERD and AIU and summarizes recent findings on the molecular genetic mechanism of aspirin hypersensitivity.-
dc.language.isoen-
dc.subject.MESHAnti-Inflammatory Agents, Non-Steroidal-
dc.subject.MESHAspirin-
dc.subject.MESHDrug Hypersensitivity-
dc.subject.MESHHumans-
dc.titleGenetics of hypersensitivity to aspirin and nonsteroidal anti-inflammatory drugs.-
dc.typeArticle-
dc.identifier.pmid23639707-
dc.identifier.urlhttp://linkinghub.elsevier.com/retrieve/pii/S0889-8561(12)00114-2-
dc.contributor.affiliatedAuthor김, 승현-
dc.contributor.affiliatedAuthor박, 해심-
dc.type.localJournal Papers-
dc.identifier.doi10.1016/j.iac.2012.10.003-
dc.citation.titleImmunology and allergy clinics of North America-
dc.citation.volume33-
dc.citation.number2-
dc.citation.date2013-
dc.citation.startPage177-
dc.citation.endPage194-
dc.identifier.bibliographicCitationImmunology and allergy clinics of North America, 33(2). : 177-194, 2013-
dc.identifier.eissn1557-8607-
dc.relation.journalidJ008898561-
Appears in Collections:
Journal Papers > Hospital > Clinical Trial Center
Journal Papers > School of Medicine / Graduate School of Medicine > Allergy
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