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Risk factors for neurologic complications of hand, foot and mouth disease in the Republic of Korea, 2009.

DC Field Value Language
dc.contributor.authorKim, SJ-
dc.contributor.authorKim, JH-
dc.contributor.authorKang, JH-
dc.contributor.authorKim, DS-
dc.contributor.authorKim, KH-
dc.contributor.authorKim, YH-
dc.contributor.authorChung, JY-
dc.contributor.authorBin, JH-
dc.contributor.authorJung, da E-
dc.contributor.authorKim, HM-
dc.contributor.authorCheon, DS-
dc.contributor.authorKang, BH-
dc.contributor.authorSeo, SY-
dc.contributor.authorEnteroviruses Complications Working Group-
dc.date.accessioned2014-05-22T23:54:57Z-
dc.date.available2014-05-22T23:54:57Z-
dc.date.issued2013-
dc.identifier.issn1011-8934-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/10084-
dc.description.abstractIn 2009, the first outbreak of hand, foot and mouth disease (HFMD) or herpangina (HP) caused by enterovirus 71 occurred in the Republic of Korea. This study inquired into risk factors associated with complications of HFMD or HP. A retrospective medical records review was conducted on HFMD or HP patients for whom etiologic viruses had been verified in 2009. One hundred sixty-eight patients were examined for this investigation. Eighty patients were without complications while 88 were accompanied by complications, and 2 had expired. Enterovirus 71 subgenotype C4a was the most prevalent in number with 67 cases (54.9%). In the univariate analysis, the disease patterns of HFMD rather than HP, fever longer than 4 days, peak body temperature over 39℃, vomiting, headache, neurologic signs, serum glucose over 100 mg/dL, and having an enterovirus 71 as a causative virus were significant risk factors of the complications. After multiple logistic analysis, headache (Odds ratio [OR], 10.75; P < 0.001) and neurologic signs (OR, 42.76; P < 0.001) were found to be the most significant factors. Early detection and proper management of patients with aforementioned risk factors would be necessary in order to attain a better clinical outcome.-
dc.language.isoen-
dc.subject.MESHAdolescent-
dc.subject.MESHAdult-
dc.subject.MESHBlood Glucose/analysis-
dc.subject.MESHBody Temperature-
dc.subject.MESHEnterovirus A, Human/genetics/isolation & purification-
dc.subject.MESHFemale-
dc.subject.MESHFever/etiology-
dc.subject.MESHGenotype-
dc.subject.MESHHand, Foot and Mouth Disease/*complications/virology-
dc.subject.MESHHeadache/etiology-
dc.subject.MESHHerpangina/*complications/virology-
dc.subject.MESHHumans-
dc.subject.MESHLogistic Models-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHOdds Ratio-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHVomiting/etiology-
dc.subject.MESHYoung Adult-
dc.titleRisk factors for neurologic complications of hand, foot and mouth disease in the Republic of Korea, 2009.-
dc.typeArticle-
dc.identifier.pmid23341722-
dc.identifier.urlhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546090/-
dc.contributor.affiliatedAuthor정, 다은-
dc.type.localJournal Papers-
dc.identifier.doi10.3346/jkms.2013.28.1.120-
dc.citation.titleJournal of Korean medical science-
dc.citation.volume28-
dc.citation.number1-
dc.citation.date2013-
dc.citation.startPage120-
dc.citation.endPage127-
dc.identifier.bibliographicCitationJournal of Korean medical science, 28(1):120-127, 2013-
dc.identifier.eissn1598-6357-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Pediatrics & Adolescent Medicine
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