Cross-section imaging with M-mode as an alternative method for the measurement of brachial artery flow-mediated vasodilation.
Shin, DH; Lee, JS; Hong, JM; Kim, SY
Journal of clinical ultrasound : JCU, 41(3):158-163, 2013
Journal of clinical ultrasound : JCU
PURPOSE: Endothelial dysfunction is well known as a risk marker for initiation and progression of atherosclerosis. Flow-mediated vasodilation (FMD) of the brachial artery induced by postischemic forearm hyperemia is a widely used noninvasive method for evaluating endothelial function. M-mode ultrasonography offers high spatial and temporal resolution and is therefore suitable for diameter measurement of pulsatile vessels. We intended to compare FMD values obtained by M-mode on cross-section images and by the conventional method, ie, measurement with B-mode ultrasonography on longitudinal images.
METHODS: We recruited 37 subjects (19 women, mean age: 48.3 ± 15.2 years; range: 23-71 years) in whom we measured the brachial artery diameters at baseline and at maximum dilation after forearm ischemia. FMD was calculated as the percentage of postischemic dilation.
RESULTS: Baseline (3.92 ± 0.72 versus 3.91 ± 0.58 mm; p = 0.97) and maximal dilated diastolic diameter (4.26 ± 0.76 versus 4.23 ± 0.61 mm; p = 0.84), FMD (8.98 ± 3.84 versus 8.14 ± 1.99%; p = 0.84), and time to maximum dilation (48.7 ± 9.0 versus 49.3 ± 6.4 seconds, p = 0.64) were not different between the two methods.
CONCLUSIONS: M-mode brachial artery diastolic and systolic diameter measurement is feasible, suitable, and accurate for the assessment of FMD without the need for electrocardiography.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
Total Visit :3,092,796
Total Download :1,262,059
Today View :381
Ajou University Medical Information & Media Center 164 Worldcup-ro Yeongtong-gu Suwon 16499 Korea / TEL : 031-219-5312 / FAX : 031-219-5314 Copyright (c) Ajou University Medical Information & Media Center All Rights Reserved. AJOU Open Repository는 국립중앙도서관 OAK 보급사업으로 구축되었습니다.