90 345

Cited 48 times in

Efficacy of 3 different steroid treatments for sudden sensorineural hearing loss: a prospective, randomized trial.

DC Field Value Language
dc.contributor.authorLim, HJ-
dc.contributor.authorKim, YT-
dc.contributor.authorChoi, SJ-
dc.contributor.authorLee, JB-
dc.contributor.authorPark, HY-
dc.contributor.authorPark, K-
dc.contributor.authorChoung, YH-
dc.date.accessioned2014-05-29-
dc.date.available2014-05-29-
dc.date.issued2013-
dc.identifier.issn0194-5998-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/10241-
dc.description.abstractOBJECTIVES: We treated patients with idiopathic sudden sensorineural hearing loss (ISSNHL) with several protocols on an outpatient department (OPD) basis. The study compared the efficacy of 3 different steroid treatments for ISSNHL.



STUDY DESIGN: A prospective randomized controlled study.



SETTING: Tertiary referral center.



METHODS: A total of 60 patients diagnosed with ISSNHL were treated through OPD. They were randomly and equally divided into 3 groups based on therapy: oral steroid for 10 days (group I), intratympanic dexamethasone injection (ITDI) 4 times (group II), and both (group III). Pure-tone average (PTA) was measured by taking 4 frequencies (0.5, 1, 2, and 3 kHz). Hearing change was evaluated by comparing pre- and posttreatment PTAs. Recovery rate was assessed by American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) Clinical Practice Guidelines.



RESULTS: The hearing gain was 12.8 ± 15.4 decibels (dB) in group I, 12.1 ± 14.6 dB in group II, and 21.9 ± 26.2 dB in group III. The recovery rate was 60% in groups I and III and 55% in group II. The overall recovery rate was 58.3% (35 of 60 patients). There was no significant difference in hearing gain and recovery rates for the 3 groups. Frequency-specific hearing gain also did not differ significantly among groups.



CONCLUSION: Three different treatment protocols (oral steroid, ITDI, or the combination) resulted in similar hearing recovery rates. Therefore, OPD-based systemic and/or local steroid therapy can be recommended as an initial treatment in ISSNHL.
-
dc.language.isoen-
dc.subject.MESHAdministration, Oral-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHAmbulatory Care/methods-
dc.subject.MESHAudiometry, Pure-Tone-
dc.subject.MESHDexamethasone/*administration & dosage-
dc.subject.MESHDose-Response Relationship, Drug-
dc.subject.MESHDrug Administration Schedule-
dc.subject.MESHDrug Therapy, Combination-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHearing Loss, Sensorineural/diagnosis/*drug therapy-
dc.subject.MESHHearing Loss, Sudden/diagnosis/*drug therapy-
dc.subject.MESHHumans-
dc.subject.MESHInjections, Intralesional-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPrednisolone/*administration & dosage-
dc.subject.MESHProspective Studies-
dc.subject.MESHRecovery of Function-
dc.subject.MESHReference Values-
dc.subject.MESHSeverity of Illness Index-
dc.subject.MESHTertiary Care Centers-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHTympanic Membrane/drug effects-
dc.subject.MESHYoung Adult-
dc.titleEfficacy of 3 different steroid treatments for sudden sensorineural hearing loss: a prospective, randomized trial.-
dc.typeArticle-
dc.identifier.pmid23077155-
dc.identifier.urlhttp://oto.sagepub.com/cgi/pmidlookup?view=long&pmid=23077155-
dc.contributor.affiliatedAuthor임, 혜진-
dc.contributor.affiliatedAuthor박, 헌이-
dc.contributor.affiliatedAuthor박, 기현-
dc.contributor.affiliatedAuthor정, 연훈-
dc.type.localJournal Papers-
dc.identifier.doi10.1177/0194599812464475-
dc.citation.titleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery-
dc.citation.volume148-
dc.citation.number1-
dc.citation.date2013-
dc.citation.startPage121-
dc.citation.endPage127-
dc.identifier.bibliographicCitationOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 148(1):121-127, 2013-
dc.identifier.eissn1097-6817-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Otolaryngology
Files in This Item:
There are no files associated with this item.

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse