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Hemophagocytosis by leukemic blasts in B lymphoblastic leukemia with t(12;21)(p13;q22); TEL-AML1 (ETV6-RUNX1): a case report.

Authors
Park, JE  | Park, IJ  | Lim, YA  | Lee, WG  | Cho, SR
Citation
Annals of clinical and laboratory science, 43(2). : 186-189, 2013
Journal Title
Annals of clinical and laboratory science
ISSN
0091-73701550-8080
Abstract
Blasts showing hemophagocytosis have been very rarely reported in acute lymphoblastic leukemia. We report a pediatric case of B lymphoblastic leukemia (BLL) with t(12;21)(p13;q22); TEL-AML1 (ETV6-RUNX1) showing erythrophagocytosis and thrombophagocytosis by leukemic blasts. About 4% of the leukemic blasts in marrow aspirate smears showed phagocytosis of erythrocytes, platelets, or nuclear remnants in a 3-year-old Korean boy with a diagnosis of BLL. Conventional cytogenetics and molecular analysis revealed the presence of t(12;21)(p13;q22); TEL-AML1 (ETV6-RUNX1). The patient responded well to chemotherapy and is in a state of complete remission.
MeSH

PMID
23694795
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Pediatrics & Adolescent Medicine
Journal Papers > School of Medicine / Graduate School of Medicine > Laboratory Medicine
Ajou Authors
박, 일중  |  박, 준은  |  이, 위교  |  임, 영애  |  조, 성란
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