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Efficacy and safety of high concentration lidocaine for trigeminal nerve block in patients with trigeminal neuralgia.

DC Field Value Language
dc.contributor.authorHan, KR-
dc.contributor.authorKim, C-
dc.contributor.authorChae, YJ-
dc.contributor.authorKim, DW-
dc.date.accessioned2011-01-07T02:11:00Z-
dc.date.available2011-01-07T02:11:00Z-
dc.date.issued2008-
dc.identifier.issn1368-5031-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/1042-
dc.description.abstractAIMS: Local anaesthetics, which act as neurolytics and Na(+) channel blockers, have been used for disrupting the neural firings in certain neuropathic pain conditions. This study was undertaken to investigate the clinical outcome of trigeminal nerve block with 10% lidocaine in the management of trigeminal neuralgia (TN).



METHODS: Thirty-five patients with primary TN received trigeminal nerve blocks with 10% lidocaine. Success was defined as complete pain relief or mild pain without medication 1 day after the treatment. We followed the patients up every 2 months assessing for pain recurrence, sensory changes and other complications for a total of 37-45 months (median 43 months).



RESULTS: Twelve of the 35 patients (34.3%) responded favourably to the treatment and were considered as success. Eleven patients experienced complete pain relief and one could tolerate pain without medication 1 day after the blocks, which lasted for 3-172 weeks. Four patients experienced mildly decreased sensation in the region of the face supplied by the nerve 1 day after the blocks; however, all recovered normal skin sensation in 6 months. There was neither allodynia nor other sensory discomfort. The pain intensity and current pain duration before treatment were significantly different between the two groups.



CONCLUSION: Trigeminal nerve block with high concentration lidocaine (10%) is capable of achieving an intermediate period of pain relief, particularly in patients with lower pain intensity and shorter pain duration prior to the procedure.
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dc.language.isoen-
dc.subject.MESHAdolescent-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAnesthetics, Local/administration & dosage*-
dc.subject.MESHAnesthetics, Local/adverse effects-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHLidocaine/administration & dosage*-
dc.subject.MESHLidocaine/adverse effects-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNerve Block/adverse effects-
dc.subject.MESHNerve Block/methods*-
dc.subject.MESHPain Measurement/methods-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHTrigeminal Neuralgia/therapy*-
dc.titleEfficacy and safety of high concentration lidocaine for trigeminal nerve block in patients with trigeminal neuralgia.-
dc.typeArticle-
dc.identifier.pmid18036166-
dc.identifier.urlhttp://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=1368-5031&date=2008&volume=62&issue=2&spage=248-
dc.contributor.affiliatedAuthor한, 경림-
dc.contributor.affiliatedAuthor김, 찬-
dc.contributor.affiliatedAuthor채, 윤정-
dc.type.localJournal Papers-
dc.identifier.doi10.1111/j.1742-1241.2007.01568.x-
dc.citation.titleInternational journal of clinical practice-
dc.citation.volume62-
dc.citation.number2-
dc.citation.date2008-
dc.citation.startPage248-
dc.citation.endPage254-
dc.identifier.bibliographicCitationInternational journal of clinical practice, 62(2):248-254, 2008-
dc.identifier.eissn1742-1241-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Anesthesiology & Pain Medicine
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