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The optimum bolus dose of remifentanil to facilitate laryngeal mask airway insertion with a single standard dose of propofol at induction in children.
DC Field | Value | Language |
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dc.contributor.author | Kwak, HJ | - |
dc.contributor.author | Kim, JY | - |
dc.contributor.author | Kim, YB | - |
dc.contributor.author | Chae, YJ | - |
dc.date.accessioned | 2011-01-07T02:26:51Z | - |
dc.date.available | 2011-01-07T02:26:51Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0003-2409 | - |
dc.identifier.uri | http://repository.ajou.ac.kr/handle/201003/1046 | - |
dc.description.abstract | The purpose of this study was to determine the optimal bolus dose of remifentanil required for the successful insertion of the laryngeal mask airway during propofol induction in children without a neuromuscular blocking agent. Twenty-six paediatric patients, aged 3-10 years, requiring anaesthesia for short ambulatory surgery were recruited. A predetermined bolus dose of remifentanil was injected over 30 s, followed by propofol 2.5 mg.kg(-1) over 10 s. The bolus dose of remifentanil was determined by a modified Dixon's up-and-down method, starting from 0.5 microg.kg(-1) (0.1 microg.kg(-1) as a step size). Laryngeal mask insertion was attempted 90 s after the end of remifentanil injection and the response of patients was classified as either 'movement' or 'no movement'. The bolus dose of remifentanil at which there was a 50% probability of successful laryngeal mask insertion (ED(50)) during induction with 2.5 mg.kg(-1) propofol was 0.56 (0.07) microg.kg(-1) in children without a neuromuscular blocking agent. From probit analysis, the ED(50) and ED(95) of remifentanil were 0.52 microg.kg(-1) (95% confidence limits, 0.42-0.62 microg.kg(-1)) and 0.71 microg.kg(-1) (95% confidence limits, 0.61-1.40 microg.kg(-1)), respectively. | - |
dc.language.iso | en | - |
dc.subject.MESH | Ambulatory Surgical Procedures | - |
dc.subject.MESH | Anesthetics, Combined | - |
dc.subject.MESH | Anesthetics, Intravenous | - |
dc.subject.MESH | Blood Pressure | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Dose-Response Relationship, Drug | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Heart Rate | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Laryngeal Masks | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Piperidines | - |
dc.subject.MESH | Propofol | - |
dc.title | The optimum bolus dose of remifentanil to facilitate laryngeal mask airway insertion with a single standard dose of propofol at induction in children. | - |
dc.type | Article | - |
dc.identifier.pmid | 18557970 | - |
dc.contributor.affiliatedAuthor | 김, 종엽 | - |
dc.contributor.affiliatedAuthor | 채, 윤정 | - |
dc.type.local | Journal Papers | - |
dc.identifier.doi | 10.1111/j.1365-2044.2008.05544.x | - |
dc.citation.title | Anaesthesia | - |
dc.citation.volume | 63 | - |
dc.citation.number | 9 | - |
dc.citation.date | 2008 | - |
dc.citation.startPage | 954 | - |
dc.citation.endPage | 958 | - |
dc.identifier.bibliographicCitation | Anaesthesia, 63(9). : 954-958, 2008 | - |
dc.identifier.eissn | 1365-2044 | - |
dc.relation.journalid | J000032409 | - |
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