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Efficacy of Glycopyrrolate in Primary Hyperhidrosis Patients

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dc.contributor.authorLee, HH-
dc.contributor.authorKim, DW-
dc.contributor.authorKim, C-
dc.date.accessioned2014-07-07-
dc.date.available2014-07-07-
dc.date.issued2012-
dc.identifier.issn2005-9159-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/10470-
dc.description.abstractBackground: Primary hyperhidrosis is a disorder of excessive sweating, which shares several features with anxiety disorders and has a negative impact on a patient’s quality of life. Oral glycopyrrolate is one of the treatments available. There are a few published studies on the use of glycopyrrolate given orally in the treatment of hyperhidrosis.



Methods: Thies is study was a review of case notes in a series of 36 patients with primary hyperhidrosis. We made a comparison between the Keller’s scale score of a pre-glycopyrrolate medication group and the Keller’s scale score f a post-glycopyrrolate medication group. The Milanez de Campos score, Short Form_36 (SF-36) score, Beck Depression Inventory (BDI) score, Beck Anxiety Inventory (BAI) score, and autonomic nervous system (ANS) scale score were also compared between the two groups.



Results: In the post-glycopyrrolate medication group, there were declines in Keller’s scale, and Milanez de Campos scale score and BAI score (P < 0.001). In addition, there were increases in SF_36 score in the post-glycopyrrolate medication group (P = 0.03) However, no changes were seen in, BDI score and ANS score in the post-glycopyrrolate medication group (P < 0.001).



Conclusions: Glycopyrrolate is an effective initial method of treating primary hyperhidrosis that, reduces anxiety and improve patients’ quality of life.
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dc.language.isoen-
dc.titleEfficacy of Glycopyrrolate in Primary Hyperhidrosis Patients-
dc.typeArticle-
dc.identifier.urlhttp://www.epain.org/journal/view.html?uid=1212&start=&sort=Regnum-0&scale=50&key=&oper=&key_word=&year1=&year2=&Vol=025&Num=01&PG=&book=Journal&mod=vol&sflag=&sub_box=Y&aut_box=Y&sos_box=&pub_box=Y&key_box=&abs_box=&year=2012-
dc.subject.keywordanticholinergic agents-
dc.subject.keywordglycopyrrolate-
dc.subject.keywordprimary hyperhidrosis-
dc.contributor.affiliatedAuthor이, 현호-
dc.contributor.affiliatedAuthor김, 도완-
dc.type.localJournal Papers-
dc.citation.titleThe Korean journal of pain-
dc.citation.volume25-
dc.citation.number1-
dc.citation.date2012-
dc.citation.startPage28-
dc.citation.endPage32-
dc.identifier.bibliographicCitationThe Korean journal of pain, 25(1):28-32, 2012-
dc.identifier.eissn2093-0569-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Anesthesiology & Pain Medicine
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