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Changes in the Microstructural and Mechanical Properties in the Medial Condyle of Human Distal Femur in Advanced Osteoarthritis

Authors
Kim, KK | Baek, MH | Won, YY
Citation
Osteoporosis, 10(2). : 61-66, 2012
Journal Title
Osteoporosis
ISSN
2093-9361
Abstract
Objectives: The purpose of this study is to analyze and compare the micro-structural and mechanical properties of subchondral trabecular bone of non-osteoarthritic and osteoarthritic distal femur using micro-images based on finite element analysis.



Materials and Methods: Twenty distal femurs were harvested from 10 cadavers. The subchondral trabeculae were obtained from the middle of the articular surface of the medial femoral condyle of distal femurs. A total of 20 specimens were scanned using the micro-CT system. Micro-CT images were converted to micro-finite element model using the mesh technique, and micro-finite element analysis was then performed for assessment of the mechanical properties.



Results: According to the results, trabecular bone of osteoarthritic distal femur showed a decrease in trabecular thickness, bone volume fraction, structure model index, and yield stress and an increase in trabecular separation and structure model index.



Conclusions: Results of bone morphometry index and strength showed greater deterioration of microstructure and decreased mechanical strength in subchondral trabeculae of the osteoarthritic group.
Keywords
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Orthopedic Surgery
Ajou Authors
원, 예연
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