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Parotid gland sparing effect by computed tomography-based modified lower field margin in whole brain radiotherapy

Cho, O; Chun, M; Park, SH; Oh, YT; Kim, MH; Park, HJ; Nam, SS; Heo, J; Noh, OK
Radiation oncology journal, 31(1):12-17, 2013
Journal Title
Radiation oncology journal
Purpose: Parotid gland can be considered as a risk organ in whole brain radiotherapy (WBRT). The purpose of this study is to evaluate the parotid gland sparing effect of computed tomography (CT)-based WBRT compared to 2-dimensional plan with conventional field margin.

Materials and Methods: From January 2008 to April 2011, 53 patients underwent WBRT using CT-based simulation. Bilateral two-field arrangement was used and the prescribed dose was 30 Gy in 10 fractions. We compared the parotid dose between 2 radiotherapy plans using different lower field margins: conventional field to the lower level of the atlas (CF) and modified field fitted to the brain tissue (MF).

Results: Averages of mean parotid dose of the 2 protocols with CF and MF were 17.4 Gy and 8.7 Gy, respectively (p 98% of prescribed dose were 99.7% for CF and 99.5% for MF.

Conclusion: Compared to WBRT with CF, CT-based lower field margin modification is a simple and effective technique for sparing the parotid gland, while providing similar dose coverage of the whole brain.
Whole brain radiotherapyParotid gland sparingXerostomiaNormal tissue complication probability
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Journal Papers > School of Medicine / Graduate School of Medicine > Radiation Oncology
AJOU Authors
전, 미선오, 영택김, 미화박, 혜진노, 오규
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