A Case of Tubulointerstitial Nephritis and Uveitis Syndrome in an Old Male

Abstract

Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare disease usually occurring in adolescent. In the present study a case of TINU syndrome in an elderly patient is described. A 69-year-old man was presented with fever, general weakness and renal insufficiency. Two weeks later the patient complained of Rt. eye pain and decreased visual acuity. An ophthalmologic examination revealed Rt. panuveitis and renal biopsy showed acute interstitial nephritis. The patient was treated with systemic corticosteroid and topical ophthalmic steroid drops. Interstitial nephritis responded to treatment but uveitis wasn't improved. So we need focal steroid injection on Rt. eye. TINU syndrome can occur in the elderly and should be considered in the differential diagnosis of uncertain tubulointerstitial nephritis.