Neonatal leukemia, which develops in first 4 weeks of life, is a rare group of hematologic neoplasm with various symptoms and prognosis. In rare cases, obstructive jaundice can be shown as initial presentation. Therefore, it is often misdiagnosed as cholestatic liver diseases. We report a case of neonatal leukemia with obstructive jaundice which was misdiagnosed as biliary atresia. This case was diagnosed with bone marrow aspirates at the age of 14th day, and the result was given that about 93% of the cells were lymphoblasts.
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