Acute Polymyositis/systemic Lupus Erythematosus Overlap Syndrome with Severe Subcutaneous Edema and Interstitial Lung Disease
Jin, UR; Kwack, KS; Park, KJ; Kwon, JE; Kim, SY; Kim, KC; Ban, GY; Jung, JY; Suh, CH; Kim, HA
Journal of rheumatic diseases, 21(1):25-29, 2014
Journal of rheumatic diseases; 대한류마티스학회지
Inflammatory myopathy is characterized by symmetrical proximal muscle weakness, elevated muscle enzyme levels and favorable response to glucocorticoids therapy. Although periorbital edema is a common manifestation of inflammatory myopathy, generalized subcutaneous edema is very rare. We report here a case of a 47-year-old female patient with acute polymyositis/systemic lupus eryth-ematosus overlap syndrome with generalized subcutaneous edema and interstitial lung disease. We aggressively treat-ed the disease with high-dose glucocorticoids, intravenous immunoglobulin, and immunosuppressive agents.
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