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Red emissive two-photon probe for real-time imaging of mitochondria trafficking.

Authors
Sarkar, AR; Heo, CH; Lee, HW; Park, KH; Suh, YH; Kim, HM
Citation
Analytical chemistry, 86(12):5638-5641, 2014
Journal Title
Analytical chemistry
ISSN
0003-27001520-6882
Abstract
Mitochondria trafficking plays an essential role for supplying energy in the neuronal system. We report here a red emissive two-photon probe for mitochondria (CMT-red) that showed high selectivity and robust staining ability for mitochondria, high photostability under a two-photon microscopy imaging condition, and low cytotoxicity. This probe can be easily loaded into live cells and tissue and used for real-time, high resolution imaging of the mitochondria trafficking in primary cortical neurons as well as in rat hippocampal tissue.
MeSH terms
AnimalsBiological TransportHippocampus/metabolismMitochondria/metabolismMolecular ProbesPhotonsRats
DOI
10.1021/ac5014805
PMID
24893806
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Pharmacology
AJOU Authors
서, 영호
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