Cited 0 times in Scipus Cited Count

Relationship between intravascular ultrasound parameters and fractional flow reserve in intermediate coronary artery stenosis of left anterior descending artery: intravascular ultrasound volumetric analysis.

DC Field Value Language
dc.contributor.authorYang, HM-
dc.contributor.authorTahk, SJ-
dc.contributor.authorLim, HS-
dc.contributor.authorYoon, MH-
dc.contributor.authorChoi, SY-
dc.contributor.authorChoi, BJ-
dc.contributor.authorJin, XJ-
dc.contributor.authorHwang, GS-
dc.contributor.authorPark, JS-
dc.contributor.authorShin, JH-
dc.date.accessioned2016-04-05T08:28:27Z-
dc.date.available2016-04-05T08:28:27Z-
dc.date.issued2014-
dc.identifier.issn1522-1946-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/12353-
dc.description.abstractOBJECTIVES: The objective of this study was to assess the relationship between

intravascular ultrasound (IVUS) parameters, including volumetric analysis, and

fractional flow reserve (FFR). BACKGROUND: Although it is known that coronary

atherosclerosis burden measured by IVUS volumetric analysis is related with

clinical outcomes, its relationship with functional significance remains unknown.

METHODS: Both IVUS and FFR were performed in 206 cases of intermediate stenosis

of the left anterior descending artery (LAD). Myocardial ischemia was assessed by

FFR and maximal hyperemia was induced by continuous intracoronary adenosine

infusion. FFR < 0.80 was considered as significant inducible myocardial ischemia.

We performed standard IVUS parameter measurements and volumetric analyses. IVUS

parameter comparison was performed in the presence (n = 90) or absence (n =116)

of significant myocardial ischemia. RESULTS: Lesions with minimal lumen area

(MLA) >/= 4.0 mm2 had FFR >/= 0.80 in 91.4% of cases, while 50.9% of lesions with

MLA < 4.0 mm2 had FFR < 0.80. The independent predictors of FFR < 0.80 were IVUS

lesion length (odds ratio [OR]: 1.1, 95% confidence interval [CI] = 1.06-1.18, P

< 0.001) and MLA significance according to the lesion location (OR: 7.01, 95% CI

= 3.09-15.92, P = 0.001). FFR correlated with plaque volume (r = -0.345, P <

0.001) and percent atheroma volume (PAV) (r = -0.398, P < 0.001). Lesions with

significant ischemia (FFR < 0.80) as compared to those with FFR > 0.80 were

associated with larger plaque volume (181.8 +/- 82.3 vs. 125.9 +/- 77.9 mm3, P <

0.001) and PAV (58.9 +/- 5.6 vs. 53.8 +/- 7.9%, P < 0.001). CONCLUSIONS: IVUS

parameters representing severity and extent of atheromatous plaque correlated

with functional significance in LAD lesions with intermediate stenosis.
-
dc.language.isoen-
dc.subject.MESHAdenosine-
dc.subject.MESHAged-
dc.subject.MESHCardiac Catheterization-
dc.subject.MESHCoronary Angiography-
dc.subject.MESHCoronary Stenosis-
dc.subject.MESHCoronary Vessels-
dc.subject.MESHFemale-
dc.subject.MESHFractional Flow Reserve, Myocardial-
dc.subject.MESHHumans-
dc.subject.MESHHyperemia-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHOdds Ratio-
dc.subject.MESHPlaque, Atherosclerotic-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHSeverity of Illness Index-
dc.subject.MESHUltrasonography, Interventional-
dc.subject.MESHVasodilator Agents-
dc.titleRelationship between intravascular ultrasound parameters and fractional flow reserve in intermediate coronary artery stenosis of left anterior descending artery: intravascular ultrasound volumetric analysis.-
dc.typeArticle-
dc.identifier.pmid23804359-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1002/ccd.25088/abstract;jsessionid=EFC73481ABF2AB76B5BCCF29137BF567.f03t02-
dc.contributor.affiliatedAuthor양, 형모-
dc.contributor.affiliatedAuthor탁, 승제-
dc.contributor.affiliatedAuthor임, 홍석-
dc.contributor.affiliatedAuthor윤, 명호-
dc.contributor.affiliatedAuthor최, 소연-
dc.contributor.affiliatedAuthor최, 병주-
dc.contributor.affiliatedAuthor황, 교승-
dc.contributor.affiliatedAuthor박, 진선-
dc.contributor.affiliatedAuthor신, 준한-
dc.type.localJournal Papers-
dc.identifier.doi10.1002/ccd.25088-
dc.citation.titleCatheterization and cardiovascular interventions-
dc.citation.volume83-
dc.citation.number3-
dc.citation.date2014-
dc.citation.startPage386-
dc.citation.endPage394-
dc.identifier.bibliographicCitationCatheterization and cardiovascular interventions, 83(3). : 386-394, 2014-
dc.identifier.eissn1522-726X-
dc.relation.journalidJ015221946-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
Files in This Item:
There are no files associated with this item.

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse