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A computerized asthma-specific quality of life: a novel tool for reflecting asthma control and predicting exacerbation.

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dc.contributor.authorKim, MA-
dc.contributor.authorYe, YM-
dc.contributor.authorPark, JW-
dc.contributor.authorLee, JH-
dc.contributor.authorLee, SK-
dc.contributor.authorKim, CW-
dc.contributor.authorJung, KS-
dc.contributor.authorKim, JH-
dc.contributor.authorYoo, HS-
dc.contributor.authorKim, SH-
dc.contributor.authorShin, YS-
dc.contributor.authorNahm, DH-
dc.contributor.authorPark, HS-
dc.contributor.authorPremier Researchers Aiming New Era in Asthma and Allergic Diseases (PRANA) Study Group-
dc.date.accessioned2016-09-26T07:24:41Z-
dc.date.available2016-09-26T07:24:41Z-
dc.date.issued2014-
dc.identifier.issn1018-2438-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/12572-
dc.description.abstractBACKGROUND: Proper assessment of health-related quality of life is essential to

achieve and maintain a controlled status in asthmatic patients. We developed our

own computerized asthma-specific quality-of-life (cA-QOL) questionnaire based on

in-depth interviews with adult asthmatic patients. In this study, we evaluated

this cA-QOL in terms of the Asthma Control Test (ACT) score and Global Initiative

for Asthma (GINA) guidelines as well as asthma exacerbation, and compared it with

the asthma-related quality-of-life questionnaire (AQLQ). METHODS: We conducted a

multicenter, prospective, observational study in 133 adult asthmatic patients

recruited from 5 university hospitals in South Korea, who were randomized into 2

groups according to the operating order of the cA-QOL and AQLQ. At every visit

(3-month interval), physicians evaluated asthma control status with monitoring

spirometry. The self-administered cA-QOL, AQLQ(S) and ACT were completed.

RESULTS: The cA-QOL scores correlated significantly with ACT and AQLQ(S) scores

(r = 0.814, p < 0.001; r = 0.900, p < 0.001). The cA-QOL score was significantly

lower where the ACT score was <19, in the patients with an uncontrolled asthma

status according to the GINA guidelines and in those with asthma exacerbation (p

< 0.001, respectively). A multivariate analysis showed that this cA-QOL was a

significant parameter associated with an uncontrolled asthma status and asthma

exacerbation (p < 0.001, p = 0.045, p = 0.019, respectively). CONCLUSION: The

cA-QOL is a valid tool for reflecting current asthma control status and for

assessment to predict the future risk of asthma exacerbation in adult asthmatics.
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dc.language.isoen-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAsthma-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPractice Guidelines as Topic-
dc.subject.MESHProspective Studies-
dc.subject.MESHQuality of Life-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHResearch Design-
dc.subject.MESHSeverity of Illness Index-
dc.subject.MESHSpirometry-
dc.subject.MESHSurveys and Questionnaires-
dc.titleA computerized asthma-specific quality of life: a novel tool for reflecting asthma control and predicting exacerbation.-
dc.typeArticle-
dc.identifier.pmid24247849-
dc.identifier.urlhttp://www.karger.com/Article/FullText/356336-
dc.contributor.affiliatedAuthor김, 미애-
dc.contributor.affiliatedAuthor예, 영민-
dc.contributor.affiliatedAuthor유, 혜수-
dc.contributor.affiliatedAuthor김, 승현-
dc.contributor.affiliatedAuthor신, 유섭-
dc.contributor.affiliatedAuthor남, 동호-
dc.contributor.affiliatedAuthor박, 해심-
dc.type.localJournal Papers-
dc.identifier.doi10.1159/000356336-
dc.citation.titleInternational archives of allergy and immunology-
dc.citation.volume163-
dc.citation.number1-
dc.citation.date2014-
dc.citation.startPage36-
dc.citation.endPage42-
dc.identifier.bibliographicCitationInternational archives of allergy and immunology, 163(1). : 36-42, 2014-
dc.identifier.eissn1423-0097-
dc.relation.journalidJ010182438-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Allergy
Journal Papers > Hospital > Clinical Trial Center
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