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Forced arterial suction thrombectomy with the penumbra reperfusion catheter in acute basilar artery occlusion: a retrospective comparison study in 2 Korean university hospitals.
|dc.description.abstract||BACKGROUND AND PURPOSE: A performance of forced arterial suction thrombectomy was
not reported for the treatment of acute basilar artery occlusion. This study
compared revascularization performance between intra-arterial fibrinolytic
treatment and forced arterial suction thrombectomy with a Penumbra reperfusion
catheter in patients with acute basilar artery occlusion. MATERIALS AND METHODS:
Fifty-seven patients with acute basilar artery occlusion were treated with
intra-arterial fibrinolysis (n = 25) or forced arterial suction thrombectomy (n =
32). Baseline characteristics, successful revascularization rate, and clinical
outcomes were compared between the groups. RESULTS: Baseline characteristics, the
frequency of patients receiving intravenous recombinant tissue plasminogen
activator, and mean time interval between symptom onset and femoral puncture did
not differ between groups. The forced arterial suction thrombectomy group had a
shorter procedure duration (75.5 minutes versus 113.3 minutes, P = .016) and
higher successful revascularization rate (88% versus 60%, P = .017) than the
fibrinolysis group. Fair outcome, indicated by a modified Rankin Scale 0-3, at 3
months was achieved in 34% of patients undergoing forced arterial suction
thrombectomy and 8% of patients undergoing fibrinolysis (P = .019), and the
mortality rate was significantly higher in the fibrinolysis group (25% versus
68%, P = .001). Multiple logistic regression analysis identified the forced
arterial suction thrombectomy method as an independent predictor of fair outcome
with adjustment for age, sex, initial NIHSS score, and the use of intravenous
recombinant tissue plasminogen activator (odds ratio, 7.768; 95% CI,
1.246-48.416; P = .028). CONCLUSIONS: In acute basilar artery occlusion, forced
arterial suction thrombectomy demonstrated a higher revascularization rate and
improved clinical outcome compared with traditional intra-arterial fibrinolysis.
Further clinical trials with the newer Penumbra catheter are warranted.
|dc.title||Forced arterial suction thrombectomy with the penumbra reperfusion catheter in acute basilar artery occlusion: a retrospective comparison study in 2 Korean university hospitals.||-|
|dc.citation.title||AJNR. American journal of neuroradiology||-|
|dc.identifier.bibliographicCitation||AJNR. American journal of neuroradiology, 35(12). : 2354-2359, 2014||-|
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