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Clinical application of sentinel lymph node mapping in colon cancer: in vivo vs. ex vivo techniques.
|dc.description.abstract||PURPOSE: Clinical usefulness of sentinel lymph node (SLN) mapping in colorectal
cancer remains controversial. The aim of this study is to evaluate the accuracy
of the SLN mapping technique using serial sectioning, and to compare the results
between ex vivo and in vivo techniques. METHODS: From February 2011 to October
2012, 34 colon cancer patients underwent SLN mapping during surgical resection.
Eleven patients were analyzed with the in vivo method, and 23 patients with the
ex vivo method. Patient characteristics and results of SLN mapping were
evaluated. RESULTS: The SLN mapping was performed in 34 patients. Mean age was
67.3 years (range, 44-81 years). Primary tumors were located in the following
sites: 13 in the right colon (38.2%) and 21 in the left colon (61.8%). SLN
mapping was performed successfully in 88.2% of the patients. There was no
significant difference in the identification rate between the two methods (90.9%
vs. 87.0%, P = 1.000). Both the mapping methods showed a low sensitivity and high
rate of skip metastasis. CONCLUSION: This study showed that SLN evaluation using
serial sectioning could not predict the nodal status with clinically acceptable
accuracy despite the high detection rate.
|dc.title||Clinical application of sentinel lymph node mapping in colon cancer: in vivo vs. ex vivo techniques.||-|
|dc.subject.keyword||Sentinel lymph node biopsy||-|
|dc.citation.title||Annals of surgical treatment and research||-|
|dc.identifier.bibliographicCitation||Annals of surgical treatment and research, 87(3). : 118-122, 2014||-|
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