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Long-term outcomes after fertility-sparing laparoscopic radical trachelectomy in young women with early-stage cervical cancer: an Asan Gynecologic Cancer Group (AGCG) study.

DC Field Value Language
dc.contributor.authorPark, JY-
dc.contributor.authorJoo, WD-
dc.contributor.authorChang, SJ-
dc.contributor.authorKim, DY-
dc.contributor.authorKim, JH-
dc.contributor.authorKim, YM-
dc.contributor.authorKim, YT-
dc.contributor.authorNam, JH-
dc.date.accessioned2016-11-08T04:58:38Z-
dc.date.available2016-11-08T04:58:38Z-
dc.date.issued2014-
dc.identifier.issn0022-4790-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/12793-
dc.description.abstractOBJECTIVES: To evaluate the long-term outcomes and risk factors for recurrence

after fertility-sparing laparoscopic radical trachelectomy (LRT) in young women

with early-stage cervical cancer. METHODS: Eighty-eight consecutive patients from

four tertiary cancer centers in Korea who had attempted fertility-sparing LRT for

early-stage cervical cancer were included in this study. RESULTS: Seventy-nine

patients completed LRT. The mean age and tumor size were 31 years (range, 20-40

years) and 1.8 cm (range, 0.4-7 cm), respectively. Twenty-nine patients had a

tumor size greater than 2 cm, 22 had deep stromal invasion greater than 50%, and

twelve had lymphovascular space invasion. After a median follow-up time of 44

months (range, 3-105 months), nine patients had recurrence and one had died of

disease. A tumor size greater than 2 cm (P = 0.039) and a depth of stromal

invasion greater than 50% (P = 0.016) were significant risk factors for

recurrence. CONCLUSIONS: This is the largest series on fertility-sparing LRT in

young women with early cervical cancer. LRT is a feasible and safe

fertility-sparing alternative to radical hysterectomy in these women. A tumor

size greater than 2 cm and a depth of stromal invasion greater than 50% were risk

factors for recurrence.
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dc.language.isoen-
dc.subject.MESHCarcinoma-
dc.subject.MESHCervix Uteri-
dc.subject.MESHChemotherapy, Adjuvant-
dc.subject.MESHFertility Preservation-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHLaparoscopy-
dc.subject.MESHHumans-
dc.subject.MESHLive Birth-
dc.subject.MESHNeoplasm Invasiveness-
dc.subject.MESHNeoplasm Recurrence, Local-
dc.subject.MESHPregnancy-
dc.subject.MESHPregnancy Rate-
dc.subject.MESHRisk Factors-
dc.subject.MESHUterine Cervical Neoplasms-
dc.titleLong-term outcomes after fertility-sparing laparoscopic radical trachelectomy in young women with early-stage cervical cancer: an Asan Gynecologic Cancer Group (AGCG) study.-
dc.typeArticle-
dc.identifier.pmid24863069-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1002/jso.23631/abstract-
dc.contributor.affiliatedAuthor장, 석준-
dc.type.localJournal Papers-
dc.identifier.doi10.1002/jso.23631-
dc.citation.titleJournal of surgical oncology-
dc.citation.volume110-
dc.citation.number3-
dc.citation.date2014-
dc.citation.startPage252-
dc.citation.endPage257-
dc.identifier.bibliographicCitationJournal of surgical oncology, 110(3). : 252-257, 2014-
dc.identifier.eissn1096-9098-
dc.relation.journalidJ000224790-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Obstetrics & Gynecology
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