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Core needle biopsy can minimise the non-diagnostic results and need for diagnostic surgery in patients with calcified thyroid nodules.

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dc.contributor.authorHa, EJ-
dc.contributor.authorBaek, JH-
dc.contributor.authorLee, JH-
dc.contributor.authorKim, JK-
dc.contributor.authorLim, HK-
dc.contributor.authorSong, DE-
dc.contributor.authorSung, TY-
dc.contributor.authorKim, WB-
dc.contributor.authorShong, YK-
dc.date.accessioned2016-11-15-
dc.date.available2016-11-15-
dc.date.issued2014-
dc.identifier.issn0938-7994-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/12867-
dc.description.abstractPURPOSE: To evaluate the role of core needle biopsy (CNB) for calcified thyroid

nodules. METHODS: Between October 2008 and July 2011, 264 patients underwent

ultrasound-guided CNB for 272 calcified thyroid nodules at our institution. We

retrospectively evaluated the incidence of technical failure, non-diagnostic

readings, and the diagnostic performance of CNB, and analysed the relationship

between the types of calcification and the CNB results. Finally, the incidence of

diagnostic surgery was calculated. RESULTS: The incidence of technical failure

was 1.1 % (3/275) and that of non-diagnostic results was 0.7 % (2/272). The

diagnostic accuracy, sensitivity, specificity, positive predictive value, and

negative predictive value of CNB were 94.7 %, 89.5 %, 100 %, 100 %, and 90.2 %,

respectively. There were no significant differences according to the

calcification subtype for either the non-diagnostic results or the incidence of

technical failure (P > 0.99 and P > 0.99). CNB could prevent diagnostic surgery

for 92.9 % (13/14) of the patients who showed more than two non-diagnostic

results in previous FNA. CONCLUSIONS: CNB can minimise the non-diagnostic results

as well as diagnostic surgery in patients with calcified thyroid nodules.

Therefore, CNB may be used as a first-line diagnostic tool for calcified thyroid

nodules rather than FNA. KEY POINTS: CNB results show the low incidence of

technical failure (1.1 %, 3/275). * CNB results show the low non-diagnostic rate

(0.7 %, 2/272). There were no significant differences according to the

calcification subtype. CNB can prevent unnecessary diagnostic surgery in 92.9 %

(13/14).
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dc.language.isoen-
dc.subject.MESHAdenoma-
dc.subject.MESHAdolescent-
dc.subject.MESHAged-
dc.subject.MESHBiopsy, Fine-Needle-
dc.subject.MESHBiopsy, Large-Core Needle-
dc.subject.MESHCalcinosis-
dc.subject.MESHCarcinoma-
dc.subject.MESHCarcinoma, Squamous Cell-
dc.subject.MESHHumans-
dc.subject.MESHImage-Guided Biopsy-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHSensitivity and Specificity-
dc.subject.MESHThyroid Neoplasms-
dc.subject.MESHThyroid Nodule-
dc.subject.MESHUltrasonography, Interventional-
dc.titleCore needle biopsy can minimise the non-diagnostic results and need for diagnostic surgery in patients with calcified thyroid nodules.-
dc.typeArticle-
dc.identifier.pmid24604217-
dc.identifier.urlhttp://link.springer.com/article/10.1007%2Fs00330-014-3123-z-
dc.contributor.affiliatedAuthor하, 은주-
dc.type.localJournal Papers-
dc.identifier.doi10.1007/s00330-014-3123-z-
dc.citation.titleEuropean radiology-
dc.citation.volume24-
dc.citation.number6-
dc.citation.date2014-
dc.citation.startPage1403-
dc.citation.endPage1409-
dc.identifier.bibliographicCitationEuropean radiology, 24(6). : 1403-1409, 2014-
dc.identifier.eissn1432-1084-
dc.relation.journalidJ009387994-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Radiology
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