Performance evaluation of Samsung LABGEO(HC10) Hematology Analyzer.

Abstract

CONTEXT: The Samsung LABGEO(HC10) Hematology Analyzer (LABGEO(HC10)) is a

recently developed automated hematology analyzer that uses impedance

technologies. The analyzer provides 18 parameters including 3-part differential

at a maximum rate of 80 samples per hour. OBJECTIVE: To evaluate the performance

of the LABGEO(HC10). DESIGN: We evaluated precision, linearity, carryover, and

relationship for complete blood cell count parameters between the LABGEO(HC10)

and the LH780 (Beckman Coulter Inc) in a university hospital in Korea according

to the Clinical and Laboratory Standards Institute guidelines. Sample stability

and differences due to the anticoagulant used (K(2)EDTA versus K(3)EDTA) were

also evaluated. RESULTS: The LABGEO(HC10) showed linearity over a wide range and

minimal carryover (<1%) for white blood cell, hemoglobin, red blood cell, and

platelet parameters. Correlation between the LABGEO(HC10) and the LH780 was good

for all complete blood cell count parameters (R > 0.92) except for mean

corpuscular hemoglobin concentration. The bias estimated was acceptable for all

parameters investigated except for monocyte count. Most parameters were stable

until 24 hours both at room temperature and at 4 degrees C. The difference by

anticoagulant type was statistically insignificant for all parameters except for

a few red cell parameters. CONCLUSIONS: The accurate results achievable and

simplicity of operation make the unit recommendable for small to medium-sized

laboratories.