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A new subtype classification of ischemic stroke based on treatment and etiologic mechanism.

Authors
Han, SW; Kim, SH; Lee, JY; Chu, CK; Yang, JH; Shin, HY; Nam, HS; Lee, BI; Heo, JH
Citation
European neurology, 57(2):96-102, 2007
Journal Title
European neurology
ISSN
0014-30221421-9913
Abstract
A new subtype classification of ischemic stroke was developed to reflect recent therapeutic strategies as well as evolving concepts of stroke definitions and mechanisms. In 200 consecutive patients with acute ischemic stroke, the inter-rater reliability and proportion of subtypes of the new classification system were assessed and compared with those of the Trial of ORG 10172 in the Acute Stroke Treatment (TOAST) classification. The most frequent subtype of the new classification was atherothrombosis (n = 80, 40%), followed by stroke of undetermined etiology (n = 54, 27%), small artery disease (n = 33, 16.5%), cardioembolism (n = 26, 13%), and stroke of other determined etiology (n = 7, 3.5%). Three raters agreed to the stroke subtype diagnosis in 165 out of 200 cases and the overall kappa value was excellent (kappa = 0.82). The new classification system for brain infarction was easy to use and had high inter-rater reliability.
MeSH terms
AdultAgedAged, 80 and overFemaleHumansIntracranial Arteriosclerosis/complicationsIntracranial Arteriosclerosis/pathologyIntracranial Embolism/complicationsIntracranial Embolism/pathologyIntracranial Thrombosis/complicationsIntracranial Thrombosis/pathologyMaleMiddle AgedObserver VariationRisk FactorsStroke/classification*Stroke/etiology*Stroke/therapy
DOI
10.1159/000098059
PMID
17179712
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Neurology
AJOU Authors
남효석
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