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Role of aggressive surgical cytoreduction in advanced ovarian cancer.

Authors
Chang, SJ  | Bristow, RE | Chi, DS | Cliby, WA
Citation
Journal of gynecologic oncology, 26(4). : 336-342, 2015
Journal Title
Journal of gynecologic oncology
ISSN
2005-03802005-0399
Abstract
Ovarian cancer is the eighth most frequent cancer in women and is the most lethal gynecologic malignancy worldwide. The majority of ovarian cancer patients are newly diagnosed presenting with advanced-stage disease. Primary cytoreductive surgery and adjuvant taxane- and platinum-based combination chemotherapy are the standard treatment for advanced ovarian cancer. A number of studies have consistently shown that successful cytoreductive surgery and the resultant minimal residual disease are significantly associated with survival in patients with this disease. Much has been written and even more debated regarding the competing perspectives of biology of ovarian cancer versus the value of aggressive surgical resection. This review will focus on the current evidences and outcomes supporting the positive impact of aggressive surgical effort on survival in the primary management of ovarian cancer.
MeSH

DOI
10.3802/jgo.2015.26.4.336
PMID
26197773
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Obstetrics & Gynecology
Ajou Authors
장, 석준
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