157 245

Cited 36 times in

Odour identification test and its relation to cardiac 123I-metaiodobenzylguanidine in patients with drug induced parkinsonism.

Authors
Lee, PH; Yeo, SH; Yong, SW; Kim, YJ
Citation
Journal of neurology, neurosurgery, and psychiatry, 78(11):1250-1252, 2007
Journal Title
Journal of neurology, neurosurgery, and psychiatry
ISSN
0022-30501468-330X
Abstract
We investigated olfactory function and its relation to cardiac 123I-metaiodobenzylguanidine (MIBG) uptake in 15 patients with drug induced parkinsonism (DIP). The mean Cross Cultural Smell Identification (CCSI) score was significantly greater in patients with DIP than in those with Parkinson's disease (PD: 6.9 (1.6) vs 4.4 (2.2); p<0.001); however, the mean CCSI score in patients with DIP was not significantly different from controls. One patient with DIP, whose CCSI score was significantly reduced, also exhibited decreased cardiac MIBG uptake. DIP patients with CCSI scores within the normal range had normal cardiac MIBG uptake. Our study suggests that an olfactory function test may be a useful tool for detecting DIP unrelated to PD and for identifying patients with DIP who have subclinical PD.
MeSH terms
3-Iodobenzylguanidine/diagnostic useAgedDiagnosis, DifferentialFemaleFollow-Up StudiesHeart/radionuclide imagingHumansMaleMediastinum/radionuclide imagingMiddle AgedOlfaction Disorders/chemically induced*Olfaction Disorders/radionuclide imagingParkinson Disease, Secondary/chemically induced*Parkinson Disease, Secondary/radionuclide imagingSmell/drug effects*Tomography, Emission-Computed, Single-Photon*
DOI
10.1136/jnnp.2007.121285
PMID
17557797
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Neurology
AJOU Authors
이필휴용석우
Full Text Link
Files in This Item:
1250-1252.pdfDownload
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse