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Long-Term Clinical Outcomes of Final Kissing Ballooning in Coronary Bifurcation Lesions Treated With the 1-Stent Technique: Results From the COBIS II Registry (Korean Coronary Bifurcation Stenting Registry).

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dc.contributor.authorYu, CW-
dc.contributor.authorYang, JH-
dc.contributor.authorSong, YB-
dc.contributor.authorHahn, JY-
dc.contributor.authorChoi, SH-
dc.contributor.authorChoi, JH-
dc.contributor.authorLee, HJ-
dc.contributor.authorOh, JH-
dc.contributor.authorKoo, BK-
dc.contributor.authorRha, SW-
dc.contributor.authorJeong, JO-
dc.contributor.authorJeong, MH-
dc.contributor.authorYoon, JH-
dc.contributor.authorJang, Y-
dc.contributor.authorTahk, SJ-
dc.contributor.authorKim, HS-
dc.contributor.authorGwon, HC-
dc.date.accessioned2017-03-28T05:44:09Z-
dc.date.available2017-03-28T05:44:09Z-
dc.date.issued2015-
dc.identifier.issn1936-8798-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/13657-
dc.description.abstractOBJECTIVES: This study investigated the impact of final kissing ballooning (FKB) after main vessel (MV) stenting on outcomes in patients with coronary bifurcation lesions after application of the 1-stent technique.

BACKGROUND: Although FKB has been established as the standard method for bifurcation lesions treated with a 2-stent strategy, its efficacy in a 1-stent approach is highly controversial.

METHODS: This study enrolled 1,901 patients with a bifurcation lesion with a side branch diameter ≥2.3 mm, treated solely with the 1-stent technique using a drug-eluting stent from 18 centers in Korea between January 1, 2003 and December 31, 2009. The primary outcome was major adverse cardiac events (MACE)-cardiac death, myocardial infarction, or target lesion revascularization. Propensity score-matching analysis was also performed.

RESULTS: FKB was performed in 620 patients and the post minimal lumen diameter of the MV and side branch was larger in the FKB group than in the non-FKB group. During follow-up (median 36 months), the incidence of MACE (adjusted hazard ratio [HR]: 0.68, 95% confidence interval [CI]: 0.46 to 0.99; p = 0.048) was lower in the FKB group than the non-FKB group. After propensity score matching (545 pairs), the FKB group had a lower incidence of MACE (adjusted HR: 0.50, 95% CI: 0.30 to 0.85; p = 0.01), and target lesion revascularization in the MV (adjusted HR: 0.51, 95% CI: 0.28 to 0.93; p = 0.03) and both vessels (adjusted HR: 0.47, 95% CI: 0.25 to 0.90; p = 0.02) than in the non-FKB group.

CONCLUSIONS: In coronary bifurcation lesions, we demonstrated that the 1-stent technique with FKB was associated with a favorable long-term clinical outcome, mainly driven by the reduction of target lesion revascularization in the MV or both vessels as a result of an increase in minimal lumen diameter. (Korean Coronary Bifurcation Stenting Registry II [COBIS II]: NCT01642992).
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dc.language.isoen-
dc.subject.MESHAged-
dc.subject.MESHAngioplasty, Balloon, Coronary-
dc.subject.MESHChi-Square Distribution-
dc.subject.MESHCoronary Angiography-
dc.subject.MESHCoronary Artery Disease-
dc.subject.MESHDisease-Free Survival-
dc.subject.MESHDrug-Eluting Stents-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHKaplan-Meier Estimate-
dc.subject.MESHLogistic Models-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMultivariate Analysis-
dc.subject.MESHMyocardial Infarction-
dc.subject.MESHPropensity Score-
dc.subject.MESHProportional Hazards Models-
dc.subject.MESHRegistries-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHTime Factors-
dc.subject.MESHTreatment Outcome-
dc.titleLong-Term Clinical Outcomes of Final Kissing Ballooning in Coronary Bifurcation Lesions Treated With the 1-Stent Technique: Results From the COBIS II Registry (Korean Coronary Bifurcation Stenting Registry).-
dc.typeArticle-
dc.identifier.pmid26315732-
dc.identifier.urlhttps://linkinghub.elsevier.com/retrieve/pii/S1936-8798(15)00811-0-
dc.contributor.affiliatedAuthor탁, 승제-
dc.type.localJournal Papers-
dc.identifier.doi10.1016/j.jcin.2015.04.015-
dc.citation.titleJACC. Cardiovascular interventions-
dc.citation.volume8-
dc.citation.number10-
dc.citation.date2015-
dc.citation.startPage1297-
dc.citation.endPage1307-
dc.identifier.bibliographicCitationJACC. Cardiovascular interventions, 8(10). : 1297-1307, 2015-
dc.identifier.eissn1876-7605-
dc.relation.journalidJ019368798-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
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