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Thirteen-year follow-up of parasellar intravascular papillary endothelial hyperplasia successfully treated by surgical excision: case report.

Authors
Sim, SY | Lim, YC  | Won, KS | Cho, KG
Citation
Journal of neurosurgery. Pediatrics, 15(4). : 384-391, 2015
Journal Title
Journal of neurosurgery. Pediatrics
ISSN
1933-07071933-0715
Abstract
Intracranial intravascular papillary endothelial hyperplasia (IPEH) is very rare, and to our knowledge long-term follow-up results have not been previously published. An 11-year-old boy presented with a 6-month history of progressive visual impairment in the right eye. Magnetic resonance imaging revealed a well-enhanced, large parasellar mass involving the cavernous sinus, right frontal skull base, and ethmoid and sphenoid sinuses. Frontotemporal craniotomy and subtotal resection were performed, and the diagnosis of IPEH was confirmed. The mass increased in size during the following 3 months. A second operation was performed via frontotemporal craniotomy combined with a transsphenoidal approach, and gross-total resection of the tumor was achieved. Adjuvant radiotherapy (5040 cGy) and chemotherapy with interferon were administered. The patient's visual symptoms improved, and there was no recurrence during a 13-year follow-up period. The results of this case indicate that intracranial IPEH can recur with subtotal resection; however, optimal resection with multimodal adjuvant treatment can control the disease for many years, if not permanently.
MeSH

DOI
10.3171/2014.9.PEDS13518
PMID
25580513
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Neurosurgery
Ajou Authors
임, 용철
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