Cited 15 times in

Predictors of Asthma Control by Stepwise Treatment in Elderly Asthmatic Patients.

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dc.contributor.authorBan, GY-
dc.contributor.authorYe, YM-
dc.contributor.authorLee, Y-
dc.contributor.authorKim, JE-
dc.contributor.authorNam, YH-
dc.contributor.authorLee, SK-
dc.contributor.authorKim, JH-
dc.contributor.authorJung, KS-
dc.contributor.authorKim, SH-
dc.contributor.authorPark, HS-
dc.contributor.authorPremier Researchers Aiming New Era in Asthma and Allergic Diseases (PRANA) Study Group-
dc.date.accessioned2017-03-31T10:41:20Z-
dc.date.available2017-03-31T10:41:20Z-
dc.date.issued2015-
dc.identifier.issn1011-8934-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/13739-
dc.description.abstractThe geriatric population is increasing, and asthma severity increases with age. We determined the predictors of asthma control, exacerbation, and the factors that affect asthma-specific quality of life (A-QOL) in elderly asthmatic patients. This was a prospective, multicenter, real-life study for 6 months with stepwise pharmacologic treatment based on the Global Initiative for Asthma (GINA) guideline. A total of 296 asthmatic patients aged ≥ 60 yr were recruited from 5 university centers in Korea. The improved-asthma control group was defined as the group of patients who maintained well-controlled or improved disease and the not-improved asthma control group was defined as the remaining patients. Fewer number of medications for comorbidities (2.8 ± 3.3 in the improved vs. 4.5 ± 4.4 in the control) and higher physical functioning (PF) scale (89.8 ± 14.2 in the improved vs. 82.0 ± 16.4 in the control) were significant predictors in the improved-asthma control group (OR = 0.863, P = 0.004 and OR = 1.028, P = 0.018, respectively). An asthma control test (ACT) score of ≤ 19 at baseline was a significant predictor of asthma exacerbation (OR = 3.938, P = 0.048). Asthma duration (F = 5.656, P = 0.018), ACT score (F = 12.237, P = 0.001) at baseline, and the presence of asthma exacerbation (F = 5.565, P = 0.019) were significant determinants of changes in A-QOL. The number of medications for comorbidities and performance status determined by the PF scale may be important parameters for assessing asthma control in elderly asthmatic patients.-
dc.language.isoen-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHAnti-Asthmatic Agents/administration & dosage-
dc.subject.MESHAsthma/diagnosis-
dc.subject.MESHAsthma/epidemiology-
dc.subject.MESHAsthma/therapy-
dc.subject.MESHCritical Pathways/statistics & numerical data-
dc.subject.MESHDose-Response Relationship, Drug-
dc.subject.MESHFemale-
dc.subject.MESHGeriatric Assessment/methods-
dc.subject.MESHGeriatric Assessment/statistics & numerical data-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHOutcome Assessment (Health Care)/methods-
dc.subject.MESHQuality of Life-
dc.subject.MESHReproducibility of Results-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHSensitivity and Specificity-
dc.subject.MESHTreatment Outcome-
dc.titlePredictors of Asthma Control by Stepwise Treatment in Elderly Asthmatic Patients.-
dc.typeArticle-
dc.identifier.pmid26240480-
dc.identifier.urlhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520933/-
dc.contributor.affiliatedAuthor반, 가영-
dc.contributor.affiliatedAuthor예, 영민-
dc.contributor.affiliatedAuthor이, 윤환-
dc.contributor.affiliatedAuthor박, 해심-
dc.type.localJournal Papers-
dc.identifier.doi10.3346/jkms.2015.30.8.1042-
dc.citation.titleJournal of Korean medical science-
dc.citation.volume30-
dc.citation.number8-
dc.citation.date2015-
dc.citation.startPage1042-
dc.citation.endPage1047-
dc.identifier.bibliographicCitationJournal of Korean medical science, 30(8). : 1042-1047, 2015-
dc.identifier.eissn1598-6357-
dc.relation.journalidJ010118934-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Allergy
Journal Papers > School of Medicine / Graduate School of Medicine > Preventive Medicine & Public Health
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