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Comparative efficacy of radiofrequency and laser ablation for the treatment of benign thyroid nodules: systematic review including traditional pooling and bayesian network meta-analysis.

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dc.contributor.authorHa, EJ-
dc.contributor.authorBaek, JH-
dc.contributor.authorKim, KW-
dc.contributor.authorPyo, J-
dc.contributor.authorLee, JH-
dc.contributor.authorBaek, SH-
dc.contributor.authorDøssing, H-
dc.contributor.authorHegedüs, L-
dc.date.accessioned2017-04-05T06:18:32Z-
dc.date.available2017-04-05T06:18:32Z-
dc.date.issued2015-
dc.identifier.issn0021-972X-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/13782-
dc.description.abstractPURPOSE: To compare the efficacy of radiofrequency ablation (RFA) and laser ablation (LA) for treatment of benign solid thyroid nodules, using a systematic review including traditional pooling and Bayesian network meta-analysis.

MATERIALS AND METHODS: A comprehensive literature search in PubMed-MEDLINE, EMBASE, and the Cochrane Library databases identified prospective studies evaluating the percentage mean change [absolute mean change (mL)] in nodule volume after RFA or LA. Studies from January 1, 2000, to November 1, 2013, were included. Review of 128 potential papers, including a full-text review of 33, identified 10 eligible papers covering a total of 184 patients for meta-analysis. The percentage mean change [absolute mean change] in nodule volume over a 6-month follow-up was compared between RFA and LA.

RESULTS: Based on the traditional frequentist approach, the pooled percentage mean changes (95% confidence interval) of RFA and LA were 76.1% (70.1-82.1) and 49.9% (41.4-58.5), respectively, and the pooled absolute mean changes (95% confidence interval) of RFA and LA were 8.9 mL (6.6-11.2) and 5.2 mL (4.3-6.1), respectively. Based on the Bayesian network meta-analysis, RFA achieved a larger pooled percentage mean change (95% credible interval) and absolute mean change (95% credible interval) compared to LA [77.8% (67.7-88.0) vs 49.5% (26.7-72.4), and 9.2 mL (5.8-11.9) vs 5.3 mL (2.1-8.5), respectively]. The RFA group has the highest probability of having the most efficacious treatment (98.7%). There were no major complications after either RFA or LA.

CONCLUSIONS: RFA appears to be superior to LA in reducing benign solid thyroid nodule volume, despite the smaller number of treatment sessions without major side effects.
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dc.language.isoen-
dc.subject.MESHBayes Theorem-
dc.subject.MESHCatheter Ablation-
dc.subject.MESHHumans-
dc.subject.MESHLaser Therapy-
dc.subject.MESHThyroid Nodule-
dc.subject.MESHTreatment Outcome-
dc.titleComparative efficacy of radiofrequency and laser ablation for the treatment of benign thyroid nodules: systematic review including traditional pooling and bayesian network meta-analysis.-
dc.typeArticle-
dc.identifier.pmid25695887-
dc.identifier.urlhttps://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.2014-4077-
dc.contributor.affiliatedAuthor하, 은주-
dc.type.localJournal Papers-
dc.identifier.doi10.1210/jc.2014-4077-
dc.citation.titleThe Journal of clinical endocrinology and metabolism-
dc.citation.volume100-
dc.citation.number5-
dc.citation.date2015-
dc.citation.startPage1903-
dc.citation.endPage1911-
dc.identifier.bibliographicCitationThe Journal of clinical endocrinology and metabolism, 100(5). : 1903-1911, 2015-
dc.identifier.eissn1945-7197-
dc.relation.journalidJ00021972X-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Radiology
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