Cited 0 times in Scipus Cited Count

An observational study of surface versus endovascular cooling techniques in cardiac arrest patients: a propensity-matched analysis.

DC Field Value Language
dc.contributor.authorOh, SH-
dc.contributor.authorOh, JS-
dc.contributor.authorKim, YM-
dc.contributor.authorPark, KN-
dc.contributor.authorChoi, SP-
dc.contributor.authorKim, GW-
dc.contributor.authorJeung, KW-
dc.contributor.authorJang, TC-
dc.contributor.authorPark, YS-
dc.contributor.authorKyong, YY-
dc.contributor.authorKorean Hypothermia Network Investigators-
dc.date.accessioned2017-04-19-
dc.date.available2017-04-19-
dc.date.issued2015-
dc.identifier.issn1364-8535-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/13888-
dc.description.abstractINTRODUCTION: Various methods and devices have been described for cooling after cardiac arrest, but the ideal cooling method remains unclear. The aim of this study was to compare the neurological outcomes, efficacies and adverse events of surface and endovascular cooling techniques in cardiac arrest patients.

METHODS: We performed a multicenter, retrospective, registry-based study of adult cardiac arrest patients treated with therapeutic hypothermia presenting to 24 hospitals across South Korea from 2007 to 2012. We included patients who received therapeutic hypothermia using overall surface or endovascular cooling devices and compared the neurological outcomes, efficacies and adverse events of both cooling techniques. To adjust for differences in the baseline characteristics of each cooling method, we performed one-to-one matching by the propensity score.

RESULTS: In total, 803 patients were included in the analysis. Of these patients, 559 underwent surface cooling, and the remaining 244 patients underwent endovascular cooling. In the unmatched cohort, a greater number of adverse events occurred in the surface cooling group. Surface cooling was significantly associated with a poor neurological outcome (cerebral performance category 3-5) at hospital discharge (p = 0.01). After propensity score matching, surface cooling was not associated with poor neurological outcome and hospital mortality [odds ratio (OR): 1.26, 95% confidence interval (CI): 0.81-1.96, p = 0.31 and OR: 0.85, 95% CI: 0.55-1.30, p = 0.44, respectively]. Although surface cooling was associated with an increased incidence of adverse events (such as overcooling, rebound hyperthermia, rewarming related hypoglycemia and hypotension) compared with endovascular cooling, these complications were not associated with surface cooling using hydrogel pads.

CONCLUSIONS: In the overall matched cohort, no significant difference in neurological outcomes and hospital morality was observed between the surface and endovascular cooling methods.
-
dc.language.isoen-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHCardiopulmonary Resuscitation-
dc.subject.MESHFemale-
dc.subject.MESHHeart Arrest-
dc.subject.MESHHospital Mortality-
dc.subject.MESHHumans-
dc.subject.MESHHypothermia, Induced-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPropensity Score-
dc.subject.MESHRegistries-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRewarming-
dc.subject.MESHTreatment Outcome-
dc.titleAn observational study of surface versus endovascular cooling techniques in cardiac arrest patients: a propensity-matched analysis.-
dc.typeArticle-
dc.identifier.pmid25880667-
dc.identifier.urlhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367874/-
dc.contributor.affiliatedAuthor김, 기운-
dc.type.localJournal Papers-
dc.identifier.doi10.1186/s13054-015-0819-7-
dc.citation.titleCritical care (London, England)-
dc.citation.volume19-
dc.citation.date2015-
dc.citation.startPage85-
dc.citation.endPage85-
dc.identifier.bibliographicCitationCritical care (London, England), 19. : 85-85, 2015-
dc.identifier.eissn1466-609X-
dc.relation.journalidJ013648535-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Emergency Medicine
Files in This Item:
25880667.pdfDownload

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse