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Hyperosmotic polydixylitol for crossing the blood brain barrier and efficient nucleic acid delivery.

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dc.contributor.authorGarg, P-
dc.contributor.authorPandey, S-
dc.contributor.authorSeonwoo, H-
dc.contributor.authorYeom, S-
dc.contributor.authorChoung, YH-
dc.contributor.authorCho, CS-
dc.contributor.authorChoung, PH-
dc.contributor.authorHoon Chung, J-
dc.date.accessioned2017-04-25T23:06:42Z-
dc.date.available2017-04-25T23:06:42Z-
dc.date.issued2015-
dc.identifier.issn1359-7345-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/13921-
dc.description.abstractHere, we introduce a polydixylitol based highly osmotic polymer that not only transmigrates the BBB by intra-arterial infusion of osmotic polyol but also triggers cellular uptake via modulation of caveolae mediated endocytosis.-
dc.language.isoen-
dc.subject.MESHAnimals-
dc.subject.MESHBlood-Brain Barrier-
dc.subject.MESHCaveolae-
dc.subject.MESHEndocytosis-
dc.subject.MESHMice-
dc.subject.MESHMice, Inbred BALB C-
dc.subject.MESHMice, Nude-
dc.subject.MESHMolecular Structure-
dc.subject.MESHNucleic Acids-
dc.subject.MESHOsmotic Pressure-
dc.subject.MESHParticle Size-
dc.subject.MESHPolymers-
dc.subject.MESHSurface Properties-
dc.subject.MESHXylitol-
dc.titleHyperosmotic polydixylitol for crossing the blood brain barrier and efficient nucleic acid delivery.-
dc.typeArticle-
dc.identifier.pmid25645149-
dc.contributor.affiliatedAuthor정, 연훈-
dc.type.localJournal Papers-
dc.identifier.doi10.1039/c4cc09871d-
dc.citation.titleChemical communications (Cambridge, England)-
dc.citation.volume51-
dc.citation.number17-
dc.citation.date2015-
dc.citation.startPage3645-
dc.citation.endPage3648-
dc.identifier.bibliographicCitationChemical communications (Cambridge, England), 51(17). : 3645-3648, 2015-
dc.identifier.eissn1364-548X-
dc.relation.journalidJ013597345-
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Journal Papers > School of Medicine / Graduate School of Medicine > Otolaryngology
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