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Diagnosis of Clinically Significant Portal Hypertension in Patients with Cirrhosis: Splenic Arterial Resistive Index versus Liver Stiffness Measurement

Authors
Lee, CM | Jeong, WK | Lim, S | Kim, Y | Kim, J  | Kim, TY | Sohn, JH
Citation
Ultrasound in medicine & biology, 42(6). : 1312-1320, 2016
Journal Title
Ultrasound in medicine & biology
ISSN
0301-56291879-291X
Abstract
The purpose of the present study is to compare the diagnostic accuracy of the splenic arterial resistive index (SARI) with that of liver stiffness measurement (LSM) for identifying patients with clinically significant portal hypertension (CSPH). We included 47 patients (M:F = 37:10) who underwent Doppler ultrasonography, LSM and hepatic venous pressure gradient (HVPG) on the same day. We investigated whether the SARI and LSM were correlated with the HVPG, and compared area under the curve (AUC) values for the abilities of SARI and LSM to diagnose CSPH. We also performed a sub-group analysis. The SARI and LSM were all moderately correlated with HVPG overall in patients. The AUC of SARI and LSM were 0.873 and 0.745, respectively. In patients without splenomegaly, SARI was strongly correlated with HVPG (r = 0.830), but LSM was moderately correlated with HVPG (r = 0.601). The AUC was also higher for SARI than for LSM. Therefore, SARI is potentially an excellent non-invasive measurement method for diagnosing CSPH, especially those without splenomegaly.
MeSH

DOI
10.1016/j.ultrasmedbio.2016.01.026
PMID
27045219
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Radiology
Ajou Authors
김, 진우
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