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Differential effect of side branch intervention on long-term clinical outcomes according to side branch stenosis after main vessel stenting: Results from the COBIS (Coronary Bifurcation Stenting) Registry II

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dc.contributor.authorJang, WJ-
dc.contributor.authorPark, YH-
dc.contributor.authorHahn, JY-
dc.contributor.authorSong, YB-
dc.contributor.authorChoi, SH-
dc.contributor.authorChun, WJ-
dc.contributor.authorHyeon Oh, J-
dc.contributor.authorKoo, BK-
dc.contributor.authorRha, SW-
dc.contributor.authorJang, Y-
dc.contributor.authorTahk, SJ-
dc.contributor.authorKim, HS-
dc.contributor.authorGwon, HC-
dc.date.accessioned2018-05-04T00:24:30Z-
dc.date.available2018-05-04T00:24:30Z-
dc.date.issued2016-
dc.identifier.issn0167-5273-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/14861-
dc.description.abstractBACKGROUND: Indication of side branch (SB) intervention after main vessel (MV) stenting is not established for coronary bifurcation lesions. METHODS: We evaluated 2017 patients who were treated with 1-stent technique or MV stenting as a first strategy. Patients undergoing SB intervention after MV stenting (SB intervention group, n=929) were compared to those treated with MV stenting only (no-SB intervention group, n=1088). RESULTS: During a median follow-up of 37months, cardiac death or myocardial infarction (MI) tended to occur less frequently in the SB intervention group than in the no-SB intervention group (1.8% versus 2.9%: adjusted hazard ratio [HR] 0.53: 95% confidence interval [CI] 0.25-1.11: P=0.09). There was a significant interaction between SB intervention and SB stenosis after MV stenting (P for interaction <0.01). Among 1077 patients with diameter stenosis of SB >/=50% after MV stenting, SB intervention was associated with a lower risk of cardiac death or MI (1.2% versus 4.2%: adjusted HR 0.22: 95% CI 0.09-0.52: P<0.01). However, among 940 patients with diameter stenosis of SB <50%, there was no significant difference in cardiac death or MI between the SB intervention group and the no-SB intervention group (3.5% versus 2.2%: adjusted HR 1.36: 95% CI 0.58-3.20: P=0.48). CONCLUSIONS: The effect of SB intervention differed according to SB stenosis after MV stenting. SB intervention may reduce cardiac death or MI in bifurcation lesions with diameter stenosis of SB >/=50% after MV stenting.-
dc.language.isoen-
dc.subject.MESHAged-
dc.subject.MESHCoronary Angiography-
dc.subject.MESHCoronary Stenosis-
dc.subject.MESHCoronary Vessels-
dc.subject.MESHDeath-
dc.subject.MESHDrug-Eluting Stents-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMyocardial Infarction-
dc.subject.MESHPercutaneous Coronary Intervention-
dc.subject.MESHRegistries-
dc.subject.MESHTime Factors-
dc.subject.MESHTreatment Outcome-
dc.titleDifferential effect of side branch intervention on long-term clinical outcomes according to side branch stenosis after main vessel stenting: Results from the COBIS (Coronary Bifurcation Stenting) Registry II-
dc.typeArticle-
dc.identifier.pmid27414725-
dc.contributor.affiliatedAuthor탁, 승제-
dc.type.localJournal Papers-
dc.identifier.doi10.1016/j.ijcard.2016.07.045-
dc.citation.titleInternational journal of cardiology-
dc.citation.volume221-
dc.citation.date2016-
dc.citation.startPage471-
dc.citation.endPage477-
dc.identifier.bibliographicCitationInternational journal of cardiology, 221. : 471-477, 2016-
dc.embargo.liftdate9999-12-31-
dc.embargo.terms9999-12-31-
dc.identifier.eissn1874-1754-
dc.relation.journalidJ001675273-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
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