Kimura's disease as a solitary intrapulmonary lymphadenopathy

Abstract

Kimura's disease is a rare, benign, immune-mediated inflammatory disorder of unknown aetiology. The most common clinical manifestation is the presence of painless head and neck lymphadenopathy, but Kimura's disease rarely presents in the thoracic cavity. We report on a 38-year old woman with interlobar lymphadenopathy on contrast-enhanced chest computed tomography, which failed to be diagnosed using bronchoscopy and endobronchial ultrasound. We performed a surgical biopsy to obtain a definitive diagnosis, while simultaneously removing the lesion. The pathology showed reactive follicular hyperplasia and a heavy infiltration of eosinophils with fibrosis in the inter-follicular area consistent with Kimura's disease.