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Regional differences in vitamin D levels and incidence of food-induced anaphylaxis in South Korea

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dc.contributor.authorKim, SH-
dc.contributor.authorBan, GY-
dc.contributor.authorPark, HS-
dc.contributor.authorKim, SC-
dc.contributor.authorYe, YM-
dc.date.accessioned2018-05-04T00:26:21Z-
dc.date.available2018-05-04T00:26:21Z-
dc.date.issued2016-
dc.identifier.issn1081-1206-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/15121-
dc.description.abstractBACKGROUND: Previous studies have suggested low vitamin D as a potential risk factor for food allergy/anaphylaxis. However, few studies have investigated the association between vitamin D and food-induced anaphylaxis (FIA) in South Korea. OBJECTIVE: To examine regional differences in serum vitamin D levels and FIA incidence. METHODS: We used nationwide data collected from 2011 to 2013. Data on vitamin D were obtained from the Korea National Health and Nutrition Examination Survey: data on FIA were obtained from the Health Insurance and Assessment Service. Districts were grouped into region 1 (lower solar radiation) and region 2 (higher solar radiation). We examined differences in FIA incidence and vitamin D levels between the regions, adjusting for age. RESULTS: The study included 2,814 patients with FIA and 15,367 people with available serum vitamin D measurements. Age-adjusted FIA incidence was 2.2 per 100,000 person-years in region 1 and 1.8 per 100,000 person-years in region 2 (relative risk, 1.23: 95% confidence interval, 1.09-1.39). Age-adjusted serum vitamin D levels were 16.5 ng/mL in region 1 and 17.8 ng/mL in region 2 (mean difference, 1.3 ng/mL: 95% confidence interval, 0.9-1.9). After stratification by age, sex, and area of residence, region 1 still had higher FIA incidence and lower vitamin D levels than region 2. CONCLUSION: The present study found a higher incidence of FIA in regions with lower vitamin D levels in the population. Further investigation is necessary to identify any direct associations between vitamin D and food allergy/anaphylaxis.-
dc.language.isoen-
dc.subject.MESHAdolescent-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAllergens/classification-
dc.subject.MESHAllergens/immunology-
dc.subject.MESHAnaphylaxis/blood-
dc.subject.MESHAnaphylaxis/epidemiology-
dc.subject.MESHAnaphylaxis/immunology-
dc.subject.MESHChild-
dc.subject.MESHFemale-
dc.subject.MESHFood/adverse effects-
dc.subject.MESHFood Hypersensitivity/blood-
dc.subject.MESHFood Hypersensitivity/epidemiology-
dc.subject.MESHFood Hypersensitivity/immunology-
dc.subject.MESHHumans-
dc.subject.MESHIncidence-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPublic Health Surveillance-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRisk Factors-
dc.subject.MESHRural Population-
dc.subject.MESHUrban Population-
dc.subject.MESHVitamin D/blood-
dc.subject.MESHYoung Adult-
dc.titleRegional differences in vitamin D levels and incidence of food-induced anaphylaxis in South Korea-
dc.typeArticle-
dc.identifier.pmid26803537-
dc.contributor.affiliatedAuthor반, 가영-
dc.contributor.affiliatedAuthor박, 해심-
dc.contributor.affiliatedAuthor예, 영민-
dc.type.localJournal Papers-
dc.identifier.doi10.1016/j.anai.2015.12.021-
dc.citation.titleAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology-
dc.citation.volume116-
dc.citation.number3-
dc.citation.date2016-
dc.citation.startPage237-
dc.citation.endPage243.e1-
dc.identifier.bibliographicCitationAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 116(3). : 237-243.e1, 2016-
dc.embargo.liftdate9999-12-31-
dc.embargo.terms9999-12-31-
dc.identifier.eissn1534-4436-
dc.relation.journalidJ010811206-
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Journal Papers > School of Medicine / Graduate School of Medicine > Allergy
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