Cited 0 times in Scipus Cited Count

Characteristics of infarction after encephaloduroarteriosynangiosis in young patients with moyamoya disease

DC Field Value Language
dc.contributor.authorKim, HG-
dc.contributor.authorLee, SK-
dc.contributor.authorLee, JD-
dc.date.accessioned2018-07-27T00:52:25Z-
dc.date.available2018-07-27T00:52:25Z-
dc.date.issued2017-
dc.identifier.issn1933-0707-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/15616-
dc.description.abstractOBJECTIVE: Young patients with moyamoya disease can exhibit infarction after revascularization surgery. This analysis of the characteristics of infarction after encephaloduroarteriosynangiosis (EDAS) in young patients with moyamoya disease was undertaken in an effort to elucidate the infarction mechanism.
METHODS: The authors retrospectively collected clinical information and reviewed pre- and postoperative MRI studies from cases involving patients younger than 18 years who underwent EDAS for the treatment of moyamoya disease between January 2012 and February 2015. Infarction patterns were categorized into watershed, territorial, or mixed pattern. The Wilcoxon rank sum test, chi-square test, and Fisher exact test were used to compare the clinical and imaging variables between patient groups. The characteristics of patients with and without postoperative infarction were compared using univariate and multivariate analysis. The cumulative proportion of patients without postoperative infarction according to operation stage was calculated using the Kaplan-Meier method and the resulting curves were compared using the log-rank test.
RESULTS: In 100 patients, 171 EDAS procedures had been performed. There were 38 cases of preoperative infarction in 35 patients and 20 cases of postoperative infarction in 13 patients. Territorial infarction was more frequent in the postoperative infarction group than in the preoperative infarction group (55.0% vs 37.8%, p = 0.037). Infarction was more common on the bilateral or contralateral side of the operation after first-stage EDAS (9 [75.0%] of 12 infarctions) than in the second-stage operation (2 [25.0%] of 8 infarctions), but the difference was not statistically significant (p = 0.068). The frequency of postoperative infarction was not significantly different depending on the stage of the operation (p = 0.694).
CONCLUSIONS: An acute infarction pattern after EDAS was more frequently territorial, suggesting an underlying occlusive mechanism. Operation stage did not affect the rate of postoperative infarction occurrence.
-
dc.language.isoen-
dc.subject.MESHAdolescent-
dc.subject.MESHCerebral Infarction-
dc.subject.MESHChild-
dc.subject.MESHChild, Preschool-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHInfant-
dc.subject.MESHMale-
dc.subject.MESHMoyamoya Disease-
dc.subject.MESHPostoperative Complications-
dc.subject.MESHRetrospective Studies-
dc.titleCharacteristics of infarction after encephaloduroarteriosynangiosis in young patients with moyamoya disease-
dc.typeArticle-
dc.identifier.pmid27715484-
dc.contributor.affiliatedAuthor김, 현지-
dc.type.localJournal Papers-
dc.identifier.doi10.3171/2016.7.PEDS16218-
dc.citation.titleJournal of neurosurgery. Pediatrics-
dc.citation.volume19-
dc.citation.number1-
dc.citation.date2017-
dc.citation.startPage1-
dc.citation.endPage7-
dc.identifier.bibliographicCitationJournal of neurosurgery. Pediatrics, 19(1). : 1-7, 2017-
dc.embargo.liftdate9999-12-31-
dc.embargo.terms9999-12-31-
dc.identifier.eissn1933-0715-
dc.relation.journalidJ019330707-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Radiology
Files in This Item:
There are no files associated with this item.

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse