21 107

Cited 0 times in

Anticoagulation in Patients with Liver Cirrhosis

Other Title
간경변증 환자에서 항응고제 치료
Authors
Cheong, JY
Citation
The Korean journal of gastroenterology, 70(5):218-222, 2017
Journal Title
The Korean journal of gastroenterology; Taehan Sohwagi Hakhoe chi
ISSN
1598-99922233-6869
Abstract
Cirrhotic patients have bleeding tendencies due to the lack of coagulation factors and thrombocytopenia. However, decreased levels of procoagulants are also accompanied by decreased levels of natural anticoagulants. However, there have been contrasting reports. It has been reported that patients with cirrhosis are at risk for thrombotic complications, including portal vein thrombosis and venous thromboembolism. Physicians consider active anticoagulation for prophylaxis and treatment of portal vein thrombosis and/or venous thromboembolism in cirrhotic patients with high risk of thrombosis. Concurrently, there are safety concerns regarding the risk of bleeding from anticoagulants in people with advanced liver disease. Further prospective studies are required to determine not only if cirrhotic patients benefit from receiving anticoagulation therapy for preventing thrombotic complications, but also to determine which prophylactic regimen is most appropriate.
MeSH terms
Anticoagulants/therapeutic use*Antithrombin III/metabolismHeparin, Low-Molecular-Weight/therapeutic useHumansLiver Cirrhosis/complications*Liver Cirrhosis/diagnosisLiver Cirrhosis/metabolismProtein C/metabolismVenous Thromboembolism/complicationsVenous Thromboembolism/diagnosisVenous Thromboembolism/drug therapy*Warfarin/therapeutic use
DOI
10.4166/kjg.2017.70.5.218
PMID
29161790
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Gastroenterology
AJOU Authors
정, 재연
Files in This Item:
29161790.pdfDownload
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse