14 26

Cited 2 times in

Relationships between oral MUC1 expression and salivary hormones in burning mouth syndrome

DC Field Value Language
dc.contributor.authorKang, JH-
dc.contributor.authorKim, YY-
dc.contributor.authorChang, JY-
dc.contributor.authorKho, HS-
dc.date.accessioned2018-10-04T06:13:53Z-
dc.date.available2018-10-04T06:13:53Z-
dc.date.issued2017-
dc.identifier.issn00039969-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/16385-
dc.description.abstractOBJECTIVES: To investigate possible relationships among oral mucosal epithelial MUC1 expression, salivary female gonadal hormones and stress markers, and clinical characteristics in patients with burning mouth syndrome (BMS).
DESIGN: Thirty post-menopausal female patients with BMS (60.0+/-5.0 years) were included. Clinical and psychological evaluations were performed and the expression level of oral mucosal epithelial MUC1 was analyzed. The levels of cortisol, dehydroepiandrosterone (DHEA), 17beta-estradiol, progesterone, chromogranin A, and blood contamination were determined from unstimulated whole saliva (UWS) and stimulated whole saliva (SWS) samples.
RESULTS: Salivary progesterone level had significant positive correlations with oral mucosal epithelial MUC1 expression level and with salivary cortisol and DHEA levels. The salivary level of 17beta-estradiol showed significant positive correlations with period of symptom duration, severity of effects of oral complaints on daily life, and results from psychological evaluations. Cortisol level in UWS and cortisol/DHEA ratio in UWS and SWS had negative correlations with severity of oral burning sensation significantly. The severity of taste disturbance had positive correlations with results from psychometry significantly.
CONCLUSION: Dysregulated psychoendocrinological interactions might affect oral mucosal MUC1 expression and severity of oral burning sensation in post-menopausal BMS patients.
-
dc.language.isoen-
dc.subject.MESHBurning Mouth Syndrome/metabolism*-
dc.subject.MESHBurning Mouth Syndrome/psychology-
dc.subject.MESHDehydroepiandrosterone/metabolism-
dc.subject.MESHEstradiol/metabolism*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHHydrocortisone/metabolism-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMucin-1/metabolism*-
dc.subject.MESHPain Measurement-
dc.subject.MESHPostmenopause-
dc.subject.MESHProgesterone/metabolism*-
dc.subject.MESHReal-Time Polymerase Chain Reaction-
dc.subject.MESHSaliva/chemistry*-
dc.titleRelationships between oral MUC1 expression and salivary hormones in burning mouth syndrome-
dc.typeArticle-
dc.identifier.pmid28199919-
dc.contributor.localId111118-
dc.contributor.affiliatedAuthor강, 정현-
dc.type.localJournal Papers-
dc.identifier.doi10.1016/j.archoralbio.2017.01.022-
dc.identifier.localIdDOI-10.1016/j.archoralbio.2017.01.022-
dc.citation.titleArchives of oral biology-
dc.citation.volume78-
dc.citation.date2017-
dc.citation.startPage58-
dc.citation.endPage64-
dc.identifier.bibliographicCitationArchives of oral biology, 78:58-64, 2017-
dc.embargo.liftdate9999-12-31-
dc.embargo.terms9999-12-31-
dc.identifier.eissn18791506-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Dentistry
Files in This Item:
28199919.pdfDownload

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse