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Myocardial Mass Contributes to the Discrepancy Between Anatomic Stenosis Severity Assessed by Intravascular Ultrasound and Fractional Flow Reserve in Intermediate Lesions of the Coronary Artery

Authors
Yoon, MH  | Tahk, SJ  | Lim, HS  | Yang, HM  | Seo, KW  | Choi, BJ  | Choi, SY  | Hwang, GS  | Park, JS  | Shin, JH
Citation
Catheterization and cardiovascular interventions, 91(2). : 182-191, 2018
Journal Title
Catheterization and cardiovascular interventions
ISSN
1522-19461522-726X
Abstract
OBJECTIVES: The present study investigated the major contributors to the discrepancy between the minimal lumen area (MLA) and fractional flow reserve (FFR).
BACKGROUND: There was considerable discrepancy between MLA or diameter stenosis (DS) and FFR.
METHODS: We enrolled 744 patients with intermediate stenoses of the left anterior descending artery (LAD). Summed epicardial coronary artery length distal to the target stenosis was obtained from each longest view of the vessels on the coronary angiograms. Mismatching was defined as a lesion with FFR of >0.80 and MLA smaller than the best cut-off value (BCV) for predicting FFR of RESULTS: Summed epicardial coronary artery length was longer at the lesions of proximal LAD than that of middle LAD (380 mm +/- 82 mm vs. 341 mm +/- 80 mm, P < 0.001). Reverse mismatching was found more frequently in the proximal than middle LAD (28.3% vs. 5.5%, P < 0.001). Independent predictors of FFR CONCLUSIONS: Myocardial mass subtended by a lesion is an important factor predicting FFR
Keywords
MeSH

DOI
10.1002/ccd.27072
PMID
28568890
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
Ajou Authors
박, 진선  |  서, 경우  |  신, 준한  |  양, 형모  |  윤, 명호  |  임, 홍석  |  최, 병주  |  최, 소연  |  탁, 승제  |  황, 교승
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