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Comparison of the planned one- and elective two-stent techniques in patients with coronary bifurcation lesions with or without acute coronary syndrome from the COBIS II Registry

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dc.contributor.authorKim, MC-
dc.contributor.authorAhn, Y-
dc.contributor.authorSun Sim, D-
dc.contributor.authorJoon Hong, Y-
dc.contributor.authorHan Kim, J-
dc.contributor.authorHo Jeong, M-
dc.contributor.authorGwon, HC-
dc.contributor.authorKim, HS-
dc.contributor.authorRha, SW-
dc.contributor.authorYoon, JH-
dc.contributor.authorJang, Y-
dc.contributor.authorTahk, SJ-
dc.contributor.authorSeung, KB-
dc.date.accessioned2019-11-13T04:26:46Z-
dc.date.available2019-11-13T04:26:46Z-
dc.date.issued2018-
dc.identifier.issn1522-1946-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/17483-
dc.description.abstractOBJECTIVES: To evaluate the impacts of stent techniques on long-term clinical outcomes after percutaneous coronary intervention (PCI) using drug-eluting stents (DES) for coronary bifurcation lesions in patients with or without acute coronary syndrome (ACS).
BACKGROUND: Few studies have investigated the impacts of stent techniques for treating coronary bifurcation lesions in patients with and without ACS.
METHODS: This multicenter registry enrolled 2,897 patients undergoing PCI with DES for coronary bifurcation lesions. We investigated the impacts of planned one-stent and elective two-stent techniques in patients with (n = 1,798) and those without (n = 1,099) ACS. Primary endpoint was the incidence of 3-year target-lesion failure (TLF), defined as a composite of cardiac death, spontaneous myocardial infarction, and target-lesion revascularization.
RESULTS: The planned one-stent technique reduced TLF rate compared to elective two-stent technique in the ACS cohort (hazard ratio [HR] 0.49: 95% confidence interval [CI] 0.34-0.74: P = 0.001), and not in the non-ACS cohort (HR 0.61: 95% CI 0.35-1.06: P = 0.079). After propensity score matching, the planned one-stent technique had a significantly lower TLF rate (HR 0.47: 95% CI 0.29-0.74: P = 0.001) in patients with ACS, and it also showed a trend toward lower TLF rate with the planned one-stent technique in patients without ACS (9.0 vs. 14.5%, HR 0.59: 95% CI 0.32-1.14: P = 0.116).
CONCLUSIONS: Planned one-stenting reduced TLF in patients with ACS and it also might be beneficial in those without ACS for the treatment of coronary bifurcation lesions.
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dc.language.isoen-
dc.titleComparison of the planned one- and elective two-stent techniques in patients with coronary bifurcation lesions with or without acute coronary syndrome from the COBIS II Registry-
dc.typeArticle-
dc.identifier.pmid29573537-
dc.subject.keywordacute coronary syndrome-
dc.subject.keywordcoronary bifurcation-
dc.subject.keywordpercutaneous coronary intervention-
dc.contributor.affiliatedAuthor탁, 승제-
dc.type.localJournal Papers-
dc.identifier.doi10.1002/ccd.27551-
dc.citation.titleCatheterization and cardiovascular interventions-
dc.citation.volume92-
dc.citation.number6-
dc.citation.date2018-
dc.citation.startPage1050-
dc.citation.endPage1060-
dc.identifier.bibliographicCitationCatheterization and cardiovascular interventions, 92(6). : 1050-1060, 2018-
dc.embargo.liftdate9999-12-31-
dc.embargo.terms9999-12-31-
dc.identifier.eissn1522-726X-
dc.relation.journalidJ015221946-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
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