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Glycated hemoglobin A1c as a screening test for detecting type 2 diabetes mellitus in obese children and adolescents

DC Field Value Language
dc.contributor.authorYoon, JS-
dc.contributor.authorSo, CH-
dc.contributor.authorLee, HS-
dc.contributor.authorHwang, JS-
dc.date.accessioned2019-11-13T04:28:38Z-
dc.date.available2019-11-13T04:28:38Z-
dc.date.issued2018-
dc.identifier.issn0334-018X-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/17735-
dc.description.abstractBACKGROUND: The diagnostic cutoff points for indicators of type 2 diabetes mellitus (T2DM) in the pediatric population have not been defined thus far.
METHODS: A retrospective, single-center study was conducted from April 2003 to May 2016. We enrolled 236 overweight or obese children and adolescents aged 4-17 years. Thirty-nine (26.9%) of 145 patients had T2DM according to the oral glucose tolerance test results.
RESULTS: A glycated hemoglobin (HbA1c) level of 6.5% had a sensitivity and specificity of 87.2% and 98.5%, respectively, for detecting T2DM. The optimal HbA1c cutoff level for T2DM was >6.2% (94.7% sensitivity, 95.5% specificity).
CONCLUSIONS: We observed that the use of an HbA1c level of 6.5% had a lower sensitivity for detecting T2DM than an HbA1c level of >6.2%.
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dc.language.isoen-
dc.subject.MESHAdolescent-
dc.subject.MESHBiomarkers/analysis-
dc.subject.MESHBody Mass Index-
dc.subject.MESHChild-
dc.subject.MESHDiabetes Mellitus, Type 2/blood-
dc.subject.MESHDiabetes Mellitus, Type 2/diagnosis-
dc.subject.MESHDiabetes Mellitus, Type 2/etiology-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHGlucose Tolerance Test-
dc.subject.MESHGlycated Hemoglobin A/analysis-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMass Screening/methods-
dc.subject.MESHObesity/complications-
dc.subject.MESHOverweight/complications-
dc.subject.MESHPrediabetic State/blood-
dc.subject.MESHPrediabetic State/diagnosis-
dc.subject.MESHPrediabetic State/etiology-
dc.subject.MESHPrognosis-
dc.subject.MESHROC Curve-
dc.subject.MESHRetrospective Studies-
dc.titleGlycated hemoglobin A1c as a screening test for detecting type 2 diabetes mellitus in obese children and adolescents-
dc.typeArticle-
dc.identifier.pmid29652667-
dc.subject.keywordHbA1c-
dc.subject.keywordobesity-
dc.subject.keywordpediatrics-
dc.subject.keywordscreening-
dc.subject.keywordtype 2 diabetes-
dc.contributor.affiliatedAuthor이, 해상-
dc.contributor.affiliatedAuthor황, 진순-
dc.type.localJournal Papers-
dc.identifier.doi10.1515/jpem-2017-0463-
dc.citation.titleJournal of pediatric endocrinology & metabolism : JPEM-
dc.citation.volume31-
dc.citation.number5-
dc.citation.date2018-
dc.citation.startPage503-
dc.citation.endPage506-
dc.identifier.bibliographicCitationJournal of pediatric endocrinology & metabolism : JPEM, 31(5). : 503-506, 2018-
dc.embargo.liftdate9999-12-31-
dc.embargo.terms9999-12-31-
dc.identifier.eissn2191-0251-
dc.relation.journalidJ00334018X-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Pediatrics & Adolescent Medicine
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