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Protein-Carbohydrate Interactions

Authors
Malik, A; Baig, MH; Manavalan, B
Publication Year
2019
Citation
Encyclopedia of Bioinformatics and Computational Biology, 3:666-677, 2019
Book Title
Encyclopedia of Bioinformatics and Computational Biology
ISBN
9780128114322
Abstract
Numerous biological processes are dependent on the interaction of proteins with carbohydrates, rendering glycan-binding proteins as potential targets for new medicines. With the rapid growth in genomic data, novel computational methods can be applied to pinpoint putative carbohydrate-binding sites in proteins, for experimental validation. Here, we review the recent developments in the structure and sequence-based protein carbohydrate binding site prediction methods. An attempt has been made to show the developments and the applications for each such method in a chronological order.(p< 0.001)
Keywords
Carbohydrate binding sitesDockingForce fieldsMachine learningMolecular dynamics simulationsProtein-carbohydrate interactionsSequence-based methodsStructure-based methods
DOI
10.1016/B978-0-12-809633-8.20661-4
Appears in Collections:
Others > Book > Book
AJOU Author
Balachandran, Manavalan
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