Encyclopedia of Bioinformatics and Computational Biology, 3:666-677, 2019
Encyclopedia of Bioinformatics and Computational Biology
Numerous biological processes are dependent on the interaction of proteins with carbohydrates, rendering glycan-binding proteins as potential targets for new medicines. With the rapid growth in genomic data, novel computational methods can be applied to pinpoint putative carbohydrate-binding sites in proteins, for experimental validation. Here, we review the recent developments in the structure and sequence-based protein carbohydrate binding site prediction methods. An attempt has been made to show the developments and the applications for each such method in a chronological order.(p< 0.001)
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