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Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study

Authors
Menditto, E | Costa, E | Midao, L | Bosnic-Anticevich, S | Novellino, E | Bialek, S | Briedis, V | Mair, A | Rajabian-Soderlund, R | Arnavielhe, S | Bedbrook, A | Czarlewski, W | Annesi-Maesano, I | Anto, JM | Devillier, P | De Vries, G | Keil, T | Sheikh, A | Orlando, V | Larenas-Linnemann, D | Cecchi, L | De Feo, G | Illario, M | Stellato, C | Fonseca, J | Malva, J | Morais-Almeida, M | Pereira, AM | Todo-Bom, AM | Kvedariene, V | Valiulis, A | Bergmann, KC | Klimek, L | Mosges, R | Pfaar, O | Zuberbier, T | Cardona, V | Mullol, J | Papadopoulos, NG | Prokopakis, EP | Bewick, M | Ryan, D | Roller-Wirnsberger, RE | Tomazic, PV | Cruz, AA | Kuna, P | Samolinski, B | Fokkens, WJ | Reitsma, S | Bosse, I | Fontaine, JF | Laune, D | Haahtela, T | Toppila-Salmi, S | Bachert, C | Hellings, PW | Melen, E | Wickman, M | Bindslev-Jensen, C | Eller, E | O'Hehir, RE | Cingi, C | Gemicioglu, B | Kalayci, O | Ivancevich, JC | Bousquet, J | MASK group
Citation
Clinical and experimental allergy, 49(4). : 442-460, 2019
Journal Title
Clinical and experimental allergy
ISSN
0954-78941365-2222
Abstract
BACKGROUND: Mobile technology may help to better understand the adherence to treatment. MASK-rhinitis (Mobile Airways Sentinel NetworK for allergic rhinitis) is a patient-centred ICT system. A mobile phone app (the Allergy Diary) central to MASK is available in 22 countries.
OBJECTIVES: To assess the adherence to treatment in allergic rhinitis patients using the Allergy Diary App.
METHODS: An observational cross-sectional study was carried out on all users who filled in the Allergy Diary from 1 January 2016 to 1 August 2017. Secondary adherence was assessed by using the modified Medication Possession Ratio (MPR) and the Proportion of days covered (PDC) approach.
RESULTS: A total of 12 143 users were registered. A total of 6 949 users reported at least one VAS data recording. Among them, 1 887 users reported >/=7 VAS data. About 1 195 subjects were included in the analysis of adherence. One hundred and thirty-six (11.28%) users were adherent (MPR >/=70% and PDC /=70% and PDC = 1.50) and 176 (14.60%) were switchers. On the other hand, 832 (69.05%) users were non-adherent to medications (MPR <70%). Of those, the largest group was non-adherent to medications and the time interval was increased in 442 (36.68%) users.
CONCLUSION AND CLINICAL RELEVANCE: Adherence to treatment is low. The relative efficacy of continuous vs on-demand treatment for allergic rhinitis symptoms is still a matter of debate. This study shows an approach for measuring retrospective adherence based on a mobile app. This also represents a novel approach for analysing medication-taking behaviour in a real-world setting.
Keywords

MeSH

DOI
10.1111/cea.13333
PMID
30597673
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Allergy
Ajou Authors
박, 해심
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