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Measuring T-1 contrast in ex-vivo prostate tissue at the Earth's magnetic field

Authors
Oh, S | Han, JH  | Kwon, JE  | Shim, JH | Lee, SJ | Hwang, SM | Hilschenz, I | Kim, K
Citation
Journal of the Korean Magnetic Resonance Society, 23(1). : 12-19, 2019
Journal Title
Journal of the Korean Magnetic Resonance Society
ISSN
1226-6531
Abstract
A former study has shown that the spin-lattice relaxation time (T-1) in cancerous prostate tissue had enhanced contrast at an ultra-low magnetic field, 132 mu T. To study the field dependence and the origin of the contrast we measured T-1 in pairs of ex-vivo prostate tissues at the Earth's magnetic field. A portable and coil-based nuclear magnetic resonance (NMR) system was adopted for T-1 measurements at 40 mu T. The T-1 contrast, delta = 1 - T-1 (more cancer)/T-1(less cancer), was calculated from each pair. Additionally, we performed pathological examinations such as Gleason's score, cell proliferation index, and micro-vessel density (MVD), to quantify correlations between the pathological parameters and T-1 of the cancerous prostate tissues.
Keywords
DOI
10.6564/JKMRS.2019.23.1.012
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Pathology
Ajou Authors
권, 지은  |  한, 재호
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