0 8

Cited 0 times in

Rituximab biosimilar CT-P10 for the treatment of rheumatoid arthritis

Authors
Jung, JY; Kim, JW; Kim, HA; Suh, CH
Citation
Expert opinion on biological therapy, 19(10). : 979-986, 2019
Journal Title
Expert opinion on biological therapy
ISSN
1471-25981744-7682
Abstract
INTRODUCTION: Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by long-standing inflammation in multiple joints. Rituximab, a monoclonal antibody, which binds to CD20, is effective in suppressing disease activity and preventing joint damage in RA. CT-P10 was developed as a biosimilar of rituximab and approved for use to treat hematologic malignancies and immune diseases including RA.
AREA COVERED: This article describes the need for this biosimilar and summarizes the non-clinical studies verifying the physicochemical and biologic similarities and the clinical studies confirming the clinical similarity of CT-P10 to rituximab in patients with RA.
EXPERT OPINION: CT-P10 had been evaluated and proven the efficacy and safety in RA in Phase I and III randomized controlled trial with extension studies including a switching regimen. Therefore, CT-P10 is recommended in the treatment of RA.
Keywords
BiosimilarCT-P10rheumatoid arthritisrituximab
MeSH terms
Antibodies, Monoclonal, Murine-Derived / administration & dosage*Antigens, CD20 / geneticsAntigens, CD20 / immunologyAntirheumatic Agents / administration & dosageArthritis, Rheumatoid / drug therapy*Arthritis, Rheumatoid / geneticsArthritis, Rheumatoid / immunologyHematologic Neoplasms / drug therapyHumansRandomized Controlled Trials as Topic
DOI
10.1080/14712598.2019.1665018
PMID
31498682
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Rheumatology
AJOU Authors
정, 주양김, 지원김, 현아서, 창희
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse