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A Path Analysis of Effects of Patients' Underlying Conditions, Treatment Satisfaction, and Adherence on Quality of Life Among Korea Glaucoma Patients

Kim, CY | Park, KH | Ahn, J  | Ahn, MD | Cha, SC | Kim, HS | Kim, JM | Kim, MJ | Kim, TW | Kim, YY | Lee, JW | Park, SW | Sohn, YH | Sung, KR | Yoo, C | Cha, JH | Kim, YJ | Lee, J | Choi, J
Journal of glaucoma, 28(9). : 785-789, 2019
Journal Title
Journal of glaucoma
PRECIS: This observed patient-specific features and treatment-driven conditions that were significantly associated with the impairment of health-related quality of life (HRQOL) among glaucoma patients. The results suggest that more systematic strategies should be implemented to improve an HRQOL.
PURPOSE: To determine factors contributing to an HRQOL and assess total, direct and indirect, effects that may exist between the determinants using path analysis.
MATERIALS AND METHODS: Data were derived from previous Korea glaucoma outcomes research. A total of 847 glaucoma outpatients with RESULTS: In EQ-5D analysis, male individuals showed total effects (beta=0.102, P=0.0026), including both direct (beta=0.076, P=0.0095) and indirect effects (beta=0.0253, P=0.0020), which were mediated by treatment satisfaction in the side effects and global satisfaction categories. Higher education (beta=0.197, P=0.0020) and satisfaction in the side effect (beta=0.095, P=0.0076) and global satisfaction (beta=0.075, P=0.0414) categories were found to have direct effects on EQ-5D. For EQ-VAS, higher education levels had significant total effects (beta=0.153, P=0.0020) accounting for direct effects (beta=0.131, P=0.0030) and indirect effects (beta=0.0223, P=0.0531) through global satisfaction. In addition, male individuals had indirect effects (beta=0.274, P=0.0165), which was indirectly mediated by satisfaction in the global satisfaction category. Comorbidity (beta=-0.096, P=0.0090) and satisfaction in the effectiveness (beta=0.094, P=0.0302), convenience (beta=0.076, P=0.0390), and global satisfaction (beta =0.144, P=0.0020) categories showed indirect effect on EQ-VAS.
CONCLUSION: Higher education and better treatment satisfaction had positive effects on HRQOL both in direct and indirect ways whereas comorbidities indirectly showed negative associations with HRQOL.

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Journal Papers > School of Medicine / Graduate School of Medicine > Ophthalmology
Ajou Authors
안, 재홍
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