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Neutrophil activation in occupational asthma

Authors
Choi, Y | Lee, Y  | Park, HS
Citation
Current opinion in allergy and clinical immunology, 19(2). : 81-85, 2019
Journal Title
Current opinion in allergy and clinical immunology
ISSN
1528-40501473-6322
Abstract
PURPOSE OF REVIEW: The aim of this review is to emphasize the role of neutrophils in patients with occupational asthma. This review facilitates a better understanding, accurate diagnosis, and proper management of asthmatic reactions provoked at the workplace.
RECENT FINDINGS: Increased recruitment and infiltration of neutrophils are found in patients with occupational asthma. Activated neutrophils release several mediators including pro-inflammatory cytokines and extracellular traps, leading to stimulation of airway epithelium and other inflammatory cells.
SUMMARY: New insights into neutrophils in the pathogenesis of occupational asthma may provide a novel approach to the individual patient with occupational asthma.
Keywords
MeSH

DOI
10.1097/ACI.0000000000000507
PMID
30601150
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Allergy
Ajou Authors
박, 해심  |  이, 영수
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