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Clinical Impact of the Fracture Risk Assessment Tool on the Treatment Decision for Osteoporosis in Patients with Knee Osteoarthritis: A Multicenter Comparative Study of the Fracture Risk Assessment Tool and World Health Organization Criteria

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dc.contributor.authorKim, BY-
dc.contributor.authorKim, HA-
dc.contributor.authorJung, JY-
dc.contributor.authorChoi, ST-
dc.contributor.authorKim, JM-
dc.contributor.authorKim, SH-
dc.contributor.authorKwon, SR-
dc.contributor.authorSuh, CH-
dc.contributor.authorKim, SS-
dc.date.accessioned2022-01-14T05:19:31Z-
dc.date.available2022-01-14T05:19:31Z-
dc.date.issued2019-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/20112-
dc.description.abstractBACKGROUND: To compare the frequency of high-risk osteoporotic fracture in patients with knee OA (OA) using the fracture risk assessment tool (FRAX) and the bone mineral density (BMD).
METHODS: We retrospectively assessed 282 Korean patients with knee OA who visited five medical centers and 1165 healthy controls (HCs) aged >/=50 years without knee OA. After matching for age, sex, and body mass index, 478 subjects (239 patients with knee OA and 239 HCs) were included.
RESULTS: Based on the BMD, the frequency of osteoporosis was 40.2% in patients with knee OA and 36.4% in HCs. The predicted mean FRAX major osteoporotic fracture probabilities calculated with or without femur neck BMD differed significantly between the knee OA and HCs (6.9 +/- 3.8% versus 6.1 +/- 2.8%, p = 0.000 and 8 +/- 3.6% versus 6.8 +/- 2.3%, p < 0.001, respectively). The mean FRAX hip fracture probabilities calculated with or without femur neck BMD differed significantly in the knee OA and HCs (2.1 +/- 2.4% versus 1.7 +/- 1.8%, p = 0.006 and 3 +/- 2.3% versus 2.4 +/- 1.6%, p < 0.001, respectively).
CONCLUSION: Our study suggests that FRAX may have a clinical impact on treatment decisions to reduce osteoporotic facture in patients with knee OA.
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dc.titleClinical Impact of the Fracture Risk Assessment Tool on the Treatment Decision for Osteoporosis in Patients with Knee Osteoarthritis: A Multicenter Comparative Study of the Fracture Risk Assessment Tool and World Health Organization Criteria-
dc.typeArticle-
dc.identifier.pmid31248035-
dc.identifier.urlhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678257/-
dc.subject.keywordfracture-
dc.subject.keywordfracture risk assessment tool-
dc.subject.keywordknee osteoarthritis-
dc.subject.keywordosteoporosis-
dc.contributor.affiliatedAuthorKim, HA-
dc.contributor.affiliatedAuthorJung, JY-
dc.contributor.affiliatedAuthorSuh, CH-
dc.type.localJournal Papers-
dc.identifier.doi10.3390/jcm8070918-
dc.citation.titleJournal of clinical medicine-
dc.citation.volume8-
dc.citation.number7-
dc.citation.date2019-
dc.citation.startPage918-
dc.citation.endPage918-
dc.identifier.bibliographicCitationJournal of clinical medicine, 8(7). : 918-918, 2019-
dc.identifier.eissn2077-0383-
dc.relation.journalidJ020770383-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Rheumatology
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