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Trajectories of health-related quality of life in breast cancer patients

DC Field Value Language
dc.contributor.authorPark, JH-
dc.contributor.authorJung, YS-
dc.contributor.authorKim, JY-
dc.contributor.authorJo, Y-
dc.contributor.authorBae, SH-
dc.date.accessioned2022-10-24T05:53:41Z-
dc.date.available2022-10-24T05:53:41Z-
dc.date.issued2020-
dc.identifier.issn0941-4355-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/22363-
dc.description.abstractPURPOSE: The purpose of this study was to explore the trajectory of health-related quality of life (HRQoL) and its predictors in breast cancer patients.

METHODS: A total of 126 women with newly diagnosed breast cancer provided baseline sociodemographic and medical characteristics and then completed an HRQoL questionnaire along with self-report measures of anxiety, depression, and cancer-related fatigue prior to their first cycle of chemotherapy (baseline), after chemotherapy completion, and at 6, and 12 months after chemotherapy completion. Group-based trajectory models were constructed to identify HRQoL trajectories over time. Logistic regression analysis was used to evaluate predictors of HRQoL in distinct patient groups.

RESULTS: Group-based trajectory modeling classified two patient groups: participants with consistently medium overall HRQoL trajectories (41.1%) and participants with consistently low overall HRQoL trajectories (58.9%). Older age, perceived severe economic burden, and higher depression predicted consistently low overall HRQoL through 12 months after chemotherapy.

CONCLUSIONS: Less than half of the total number of patients maintained a medium level of overall HRQoL after diagnosis and treatment of breast cancer, and nearly 60% continued to have lower overall HRQoL even after the treatment was complete. Older participants with more severe economic burden and higher depression experienced lower and more persistent overall HRQoL; thus, these patients should be monitored and provided supportive care as a part of survivorship care.
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dc.language.isoen-
dc.subject.MESHAdult-
dc.subject.MESHAnxiety-
dc.subject.MESHBreast Neoplasms-
dc.subject.MESHDepression-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHLongitudinal Studies-
dc.subject.MESHProspective Studies-
dc.subject.MESHQuality of Life-
dc.subject.MESHSurvival Rate-
dc.titleTrajectories of health-related quality of life in breast cancer patients-
dc.typeArticle-
dc.identifier.pmid31768734-
dc.subject.keywordAdjuvant chemotherapy-
dc.subject.keywordBreast neoplasms-
dc.subject.keywordCost of illness-
dc.subject.keywordDepression-
dc.subject.keywordFatigue-
dc.subject.keywordQuality of life-
dc.contributor.affiliatedAuthorPark, JH-
dc.contributor.affiliatedAuthorJung, YS-
dc.contributor.affiliatedAuthorKim, JY-
dc.contributor.affiliatedAuthorBae, SH-
dc.type.localJournal Papers-
dc.identifier.doi10.1007/s00520-019-05184-3-
dc.citation.titleSupportive care in cancer-
dc.citation.volume28-
dc.citation.number7-
dc.citation.date2020-
dc.citation.startPage3381-
dc.citation.endPage3389-
dc.identifier.bibliographicCitationSupportive care in cancer, 28(7). : 3381-3389, 2020-
dc.embargo.liftdate9999-12-31-
dc.embargo.terms9999-12-31-
dc.identifier.eissn1433-7339-
dc.relation.journalidJ009414355-
Appears in Collections:
Journal Papers > College of Nursing Science / Graduate School of Nursing Sciences > Nursing Science
Journal Papers > School of Medicine / Graduate School of Medicine > Surgery
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