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Update on the Management of Nonsteroidal Anti-Inflammatory Drug Hypersensitivity

Authors
Yeung, WYW | Park, HS
Citation
Yonsei medical journal, 61(1). : 4-14, 2020
Journal Title
Yonsei medical journal
ISSN
0513-57961976-2437
Abstract
The clinical phenotypes of nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity are heterogeneous with various presentations including time of symptom onset, organ involvements, and underlying pathophysiology. Having a correct diagnosis can be challenging. Understanding their respective mechanisms as well as developing a comprehensive classification and diagnostic algorithm are pivotal for appropriate management strategy. Treatment modalities are based on the subtypes and severity of hypersensitivity reactions. Insights into the phenotypes and endotypes of hypersensitivity reactions enable personalized management in patients with suboptimal control of disease. This review updated the recent evidence of pathophysiology, classification, diagnostic algorithm, and management of NSAID hypersensitivity reactions.
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MeSH

DOI
10.3349/ymj.2020.61.1.4
PMID
31887794
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Allergy
Ajou Authors
박, 해심
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